IRIS
COLLINA, SIMONA
 Distribuzione geografica
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Continente #
NA - Nord America 11.484
AS - Asia 8.297
EU - Europa 7.030
SA - Sud America 1.323
Continente sconosciuto - Info sul continente non disponibili 406
AF - Africa 302
OC - Oceania 1
Totale 28.843
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Nazione #
US - Stati Uniti d'America 11.134
CN - Cina 3.910
SG - Singapore 1.710
IE - Irlanda 1.510
IT - Italia 1.027
BR - Brasile 981
HK - Hong Kong 870
RU - Federazione Russa 828
VN - Vietnam 798
DE - Germania 745
UA - Ucraina 655
FI - Finlandia 607
FR - Francia 535
GB - Regno Unito 410
IN - India 262
SE - Svezia 257
CA - Canada 189
ZA - Sudafrica 170
BD - Bangladesh 130
AR - Argentina 120
JP - Giappone 105
MX - Messico 95
IQ - Iraq 89
BE - Belgio 77
ES - Italia 70
PL - Polonia 66
EC - Ecuador 52
VE - Venezuela 49
ID - Indonesia 48
TR - Turchia 48
CO - Colombia 47
NL - Olanda 47
PK - Pakistan 40
LT - Lituania 31
AT - Austria 29
PH - Filippine 29
MA - Marocco 28
UZ - Uzbekistan 27
CZ - Repubblica Ceca 24
SA - Arabia Saudita 24
CL - Cile 21
IR - Iran 20
MY - Malesia 20
PT - Portogallo 19
AE - Emirati Arabi Uniti 18
CH - Svizzera 18
JO - Giordania 18
PY - Paraguay 17
KR - Corea 16
TN - Tunisia 16
AZ - Azerbaigian 14
CR - Costa Rica 13
EG - Egitto 13
NP - Nepal 13
PE - Perù 13
JM - Giamaica 11
KE - Kenya 11
BO - Bolivia 10
UY - Uruguay 10
AL - Albania 9
DZ - Algeria 9
IL - Israele 9
KZ - Kazakistan 9
DO - Repubblica Dominicana 8
ET - Etiopia 8
EU - Europa 8
KG - Kirghizistan 8
PA - Panama 8
BG - Bulgaria 7
CI - Costa d'Avorio 7
GR - Grecia 7
TT - Trinidad e Tobago 7
AM - Armenia 6
DK - Danimarca 6
HN - Honduras 6
HU - Ungheria 6
LB - Libano 6
LV - Lettonia 6
NO - Norvegia 6
OM - Oman 6
RO - Romania 6
SN - Senegal 6
MU - Mauritius 5
PS - Palestinian Territory 5
RS - Serbia 5
TH - Thailandia 5
AO - Angola 4
GA - Gabon 4
HR - Croazia 4
LK - Sri Lanka 4
NI - Nicaragua 4
TL - Timor Orientale 4
EE - Estonia 3
GT - Guatemala 3
GY - Guiana 3
KH - Cambogia 3
KW - Kuwait 3
LY - Libia 3
MG - Madagascar 3
MN - Mongolia 3
Totale 28.396
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Città #
Dublin 1.506
Chandler 1.365
San Jose 1.061
Ashburn 1.002
Dallas 963
Singapore 912
Beijing 859
Hong Kong 845
Jacksonville 789
Nanjing 736
Boardman 409
Council Bluffs 389
Los Angeles 329
Ho Chi Minh City 290
Ann Arbor 288
Nanchang 270
Lauterbourg 266
New York 237
Princeton 237
Helsinki 233
Lawrence 226
Munich 217
Hebei 214
Shanghai 197
Shenyang 196
Pavia 194
Wilmington 185
Changsha 174
Medford 174
Hanoi 166
Jiaxing 157
Johannesburg 151
Moscow 151
Milan 146
Tianjin 128
Hangzhou 124
Santa Clara 121
Redondo Beach 120
Buffalo 107
São Paulo 96
Tokyo 95
Orem 92
Pune 78
Toronto 76
Brussels 73
Woodbridge 68
Chennai 67
Turku 66
Seattle 61
The Dalles 55
Warsaw 55
Columbus 54
Frankfurt am Main 52
London 47
Piscataway 46
Chicago 45
Da Nang 45
Denver 44
Montreal 43
Norwalk 42
Stockholm 42
Atlanta 38
Manchester 37
Houston 34
Mexico City 34
Rio de Janeiro 34
Haiphong 33
Verona 33
Brooklyn 32
Florence 32
Poplar 30
Rome 29
Dearborn 28
Guangzhou 28
Amsterdam 27
Phoenix 27
San Francisco 27
Nuremberg 26
Fairfield 25
Falkenstein 25
Boston 24
Tashkent 24
Zhengzhou 23
Des Moines 22
Washington 22
Baghdad 21
Basingstoke 20
Mumbai 20
Naples 20
Sulaymaniyah 20
Quito 19
Biên Hòa 17
Jinan 17
Mountain View 17
Auburn Hills 16
Belo Horizonte 16
Brasília 16
Caracas 16
Curitiba 16
Hải Dương 16
Totale 18.437
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Nome #
Estrazione mediante microonde (MASE) di cumarina e composti correlati da Melilotus officinalis, una valida alternativa all'estrazione con Soxhlet e con ultrasuoni (USAE). 434
Quantitative evaluation of RC-106 antitumor activity in GBM spheroids through tumor growth inhibition modeling based on cell counts data 180
Estrazione di flavonoidi da Crataegus monogyna Jacq. mediante microonde (MASE), un'alternativa alla macerazione, all'estrazione con Soxhlet e con ultrasuoni (USAE). 172
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 172
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 165
Disegno razionale e sintesi di ligandi selettivi per il sottotipo recettoriale sigma1 164
ASSESMENT OF MARRUBIUM VULGARE L. HERBAL RAW MATERIAL QUALITY. SET UP OF A COMBINED MASE AND HPLC-UV/PAD METHODOLOGY DRIVEN BY DOE 163
A composite nanosystem as a potential tool for the local treatment of glioblastoma: Chitosan‐coated solid lipid nanoparticles embedded in electrospun nanofibers 160
Formulation of microspheres containing Crataegus monogyna extract in feed design 155
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 154
Microwave assisted synthesis of chiral pyrrolines with biological activity 152
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 149
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 148
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 148
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 148
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 148
Approaches for multi-gram scale isolation of enantiomers for drug discovery 148
SAR Evaluation of Chiral Naphthylorfines with Antinociceptive Activity 147
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 147
Sintesi parallela in soluzione di scaffolds olefinici per la preparazione di nuovi ligandi sigma 145
Dialkylaminoalkylnaphthalenes as novel opioid-like analgesics 144
Disegno razionale, sintesi e valutazione biologica di nuovi ligandi ad elevata affinità per i recettori sigma 1 a struttura fenilalchenil- e fenilalchil- amminica 144
Progettazione e Sintesi di nuovi Ligandi Sigma 142
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 142
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 142
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 141
Preparation and Configuration of Racemic and Optically Active Analgesic Cycloaminoalkiynaphthalenes 140
Estrazione di cumarina da Melilotus officinalis (L.) Pallas. 140
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 140
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 140
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 139
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 139
Novel sigma ligands: design, preparation and biological evaluation 137
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 137
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 137
Nature inspired new compounds against Leishmaniosis, from Eremurus persicus 137
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 135
Preparazione mediante reattivi supportati e riscaldamento a microonde di esteri alpha-beta-insaturi, intermedi chiave per la sintesi di nuovi ligandi sigma 134
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 134
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 134
Plasminogen Recruitment by Staphylococcus aureus SdrC Reveals a Tractable Antivirulence Target 133
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 133
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 132
Sigma receptor modulators: a patent review. 132
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 132
Alginate-based electrospun fibers for the delivery of sigma-1 receptor agonists in the treatment of spinal cord injuries 132
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 131
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 131
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 131
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 131
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 130
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 130
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 130
Synthesis and antinociceptive activity of Pyrrolidinylnaphthalenes 129
Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds 129
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 128
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 128
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 127
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 127
Derivati indolilalchilaminici. Approccio razionale alla progettazione di nuovi ligandi sigma 126
Design, synthesis and pharmacological activity of new antinociceptive agents 126
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 126
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 125
Highly diastereoselective synthesis of enantiopure naphthylaminoalcohols with analgesic properties 125
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 125
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 125
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 124
Pistagremic acid, a glucosidase inhibitor from Pistacia integerrima 123
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? 122
Efficient Microwave and Phosphane-free Synthesis of Trisubstituted Olefins via Heck Coupling 122
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 122
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition 122
Synthesis of pyrrolinylnaphthalenes and evaluation of their antinociceptive activity 121
DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance 121
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 120
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 120
A practical synthesis of (3-(phenanthren-9-yl)-4,5-dihydroisoxazol-5-yl)methyl (tert-butoxycarbonyl)-L-alaninate 120
Electrospun alginate-PEO fibers for the delivery of sigma-1 receptor agonists in the treatment of SCI: influence of PEO molecular weight on fiber production. 120
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 119
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 119
Chiral recognition of alkyl 2-aryloxypropionates by HPLC 119
Antibacterial activity and metabolite profiling of manuka honey (Lectospermum scoparium L.) submitted to in vitro simulated digestion. 118
Synthesis and SAR of Novel Sigma1 Selective Ligands 118
Chiral arylpyrrolidinols: preparation and biological profile 118
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 118
A versatile strategy for the synthesis of 4,5-dihydroxy-2,3-pentanedione (DPD) and related compounds as potential modulators of bacterial quorum sensing 118
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 117
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 117
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 117
Are sigma receptor modulators a weapon against multiple sclerosis disease? 117
A novel composite nanosystem as a potential tool for the local treatment of glioblastoma. 116
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 116
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 115
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 115
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 115
Nature aided drug discovery. Novel Compounds against Leishmaniasis from Eremurus persicus. 115
Rational Approach to the Design of Selective Sigma 1 Ligands 114
Diastereoselective synthesis of chiral nonracemic naphthylaminoalcohols with analgesic activity 114
Influence of in Vitro Simulated Gastroduodenal Digestion on Methylglyoxal Concentration of Manuka ( Lectospermum scoparium ) Honey. 114
Risoluzione di ligandi selettivi sigma1 a struttura alchilamminoalchilarilica mediante HPLC chirale e studio configurazionale 113
Totale 13.550
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Categoria #
all - tutte 115.309
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 115.309
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.133 0 16 51 19 17 36 26 76 62 45 154 631
2022/20233.922 365 345 51 273 365 410 3 207 1.714 23 111 55
2023/20241.788 209 291 52 96 152 415 106 133 9 75 124 126
2024/20254.570 106 347 126 143 195 299 262 241 1.143 162 500 1.046
2025/202610.648 847 740 1.405 1.249 1.424 473 1.876 472 903 728 274 257
2026/2027685 190 495 0 0 0 0 0 0 0 0 0 0
Totale 28.843