IRIS
COLLINA, SIMONA
 Distribuzione geografica
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Continente #
NA - Nord America 13.295
AS - Asia 8.340
EU - Europa 7.433
SA - Sud America 1.356
Continente sconosciuto - Info sul continente non disponibili 416
AF - Africa 305
OC - Oceania 1
Totale 31.146
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Nazione #
US - Stati Uniti d'America 12.720
CN - Cina 3.915
SG - Singapore 1.721
IE - Irlanda 1.513
IT - Italia 1.367
BR - Brasile 1.009
HK - Hong Kong 870
RU - Federazione Russa 842
VN - Vietnam 799
DE - Germania 746
UA - Ucraina 656
FI - Finlandia 607
FR - Francia 538
GB - Regno Unito 432
IN - India 263
CA - Canada 262
SE - Svezia 257
ZA - Sudafrica 170
BD - Bangladesh 133
AR - Argentina 120
JP - Giappone 106
MX - Messico 97
IQ - Iraq 89
BE - Belgio 78
ES - Italia 71
PL - Polonia 66
NL - Olanda 54
EC - Ecuador 52
ID - Indonesia 50
VE - Venezuela 50
TR - Turchia 49
CO - Colombia 48
PK - Pakistan 41
CR - Costa Rica 35
TT - Trinidad e Tobago 32
LT - Lituania 31
AT - Austria 29
PH - Filippine 29
MA - Marocco 28
UZ - Uzbekistan 27
CL - Cile 24
CZ - Repubblica Ceca 24
SA - Arabia Saudita 24
HN - Honduras 23
IL - Israele 22
MY - Malesia 22
NI - Nicaragua 21
GT - Guatemala 20
IR - Iran 20
JM - Giamaica 20
PT - Portogallo 19
AE - Emirati Arabi Uniti 18
CH - Svizzera 18
JO - Giordania 18
PY - Paraguay 17
KR - Corea 16
SV - El Salvador 16
TN - Tunisia 16
AZ - Azerbaigian 14
EG - Egitto 13
NP - Nepal 13
PE - Perù 13
PR - Porto Rico 13
KE - Kenya 11
AL - Albania 10
BO - Bolivia 10
CW - ???statistics.table.value.countryCode.CW??? 10
KZ - Kazakistan 10
UY - Uruguay 10
DZ - Algeria 9
GP - Guadalupe 9
DK - Danimarca 8
DO - Repubblica Dominicana 8
EE - Estonia 8
ET - Etiopia 8
EU - Europa 8
KG - Kirghizistan 8
PA - Panama 8
AM - Armenia 7
BG - Bulgaria 7
CI - Costa d'Avorio 7
GR - Grecia 7
RO - Romania 7
HU - Ungheria 6
LB - Libano 6
LV - Lettonia 6
NO - Norvegia 6
OM - Oman 6
SN - Senegal 6
MU - Mauritius 5
PS - Palestinian Territory 5
RS - Serbia 5
TH - Thailandia 5
AO - Angola 4
GA - Gabon 4
HR - Croazia 4
LK - Sri Lanka 4
TL - Timor Orientale 4
BB - Barbados 3
GY - Guiana 3
Totale 30.678
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Città #
Dublin 1.506
Chandler 1.365
Ashburn 1.359
San Jose 1.194
Dallas 974
Singapore 917
Beijing 860
Hong Kong 845
Jacksonville 791
Nanjing 736
Council Bluffs 643
Boardman 409
Los Angeles 346
Ho Chi Minh City 291
Ann Arbor 288
Nanchang 270
Lauterbourg 266
New York 240
Princeton 238
Helsinki 233
Lawrence 226
Munich 217
Hebei 214
Shanghai 198
Shenyang 196
Pavia 194
Wilmington 186
Milan 176
Changsha 174
Medford 174
Hanoi 166
Jiaxing 157
Johannesburg 151
Moscow 151
Santa Clara 141
Tianjin 128
Hangzhou 124
Redondo Beach 120
São Paulo 117
Buffalo 112
Tokyo 96
Toronto 95
Orem 92
Pune 78
Brussels 73
Rome 69
Woodbridge 69
Chennai 68
Turku 66
Seattle 64
Columbus 57
The Dalles 55
Warsaw 55
Frankfurt am Main 52
Chicago 50
Naples 50
London 47
Montreal 47
Atlanta 46
Piscataway 46
Da Nang 45
Brooklyn 44
Denver 44
Norwalk 43
Florence 42
Stockholm 42
Houston 39
Manchester 38
Phoenix 38
Verona 36
Mexico City 35
Rio de Janeiro 34
Haiphong 33
San Francisco 32
Poplar 30
Amsterdam 28
Dearborn 28
Guangzhou 28
Nuremberg 26
Washington 26
Boston 25
Fairfield 25
Falkenstein 25
San José 24
Tashkent 24
Bologna 23
Newark 23
Zhengzhou 23
Brasília 22
Des Moines 22
Baghdad 21
Managua 21
Basingstoke 20
Mumbai 20
Sulaymaniyah 20
Quito 19
Kingston 18
Biên Hòa 17
Jinan 17
Mountain View 17
Totale 19.505
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Nome #
Estrazione mediante microonde (MASE) di cumarina e composti correlati da Melilotus officinalis, una valida alternativa all'estrazione con Soxhlet e con ultrasuoni (USAE). 452
Quantitative evaluation of RC-106 antitumor activity in GBM spheroids through tumor growth inhibition modeling based on cell counts data 194
Estrazione di flavonoidi da Crataegus monogyna Jacq. mediante microonde (MASE), un'alternativa alla macerazione, all'estrazione con Soxhlet e con ultrasuoni (USAE). 194
ASSESMENT OF MARRUBIUM VULGARE L. HERBAL RAW MATERIAL QUALITY. SET UP OF A COMBINED MASE AND HPLC-UV/PAD METHODOLOGY DRIVEN BY DOE 177
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 176
A composite nanosystem as a potential tool for the local treatment of glioblastoma: Chitosan‐coated solid lipid nanoparticles embedded in electrospun nanofibers 175
SAR Evaluation of Chiral Naphthylorfines with Antinociceptive Activity 172
Disegno razionale e sintesi di ligandi selettivi per il sottotipo recettoriale sigma1 171
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 171
Progettazione e Sintesi di nuovi Ligandi Sigma 164
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 161
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 161
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 160
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 160
Microwave assisted synthesis of chiral pyrrolines with biological activity 159
Formulation of microspheres containing Crataegus monogyna extract in feed design 159
Alginate-based electrospun fibers for the delivery of sigma-1 receptor agonists in the treatment of spinal cord injuries 158
Estrazione di cumarina da Melilotus officinalis (L.) Pallas. 156
Sintesi parallela in soluzione di scaffolds olefinici per la preparazione di nuovi ligandi sigma 155
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 154
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 153
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 153
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 153
Approaches for multi-gram scale isolation of enantiomers for drug discovery 153
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 152
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 150
Plasminogen Recruitment by Staphylococcus aureus SdrC Reveals a Tractable Antivirulence Target 149
Dialkylaminoalkylnaphthalenes as novel opioid-like analgesics 149
Disegno razionale, sintesi e valutazione biologica di nuovi ligandi ad elevata affinità per i recettori sigma 1 a struttura fenilalchenil- e fenilalchil- amminica 149
Nature inspired new compounds against Leishmaniosis, from Eremurus persicus 149
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 149
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 148
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 147
Preparation and Configuration of Racemic and Optically Active Analgesic Cycloaminoalkiynaphthalenes 145
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 145
Design, synthesis and pharmacological activity of new antinociceptive agents 145
DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance 145
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 144
Sigma receptor modulators: a patent review. 143
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 143
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 142
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 142
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 142
Novel sigma ligands: design, preparation and biological evaluation 140
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 140
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 138
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 138
Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds 138
Derivati indolilalchilaminici. Approccio razionale alla progettazione di nuovi ligandi sigma 137
Preparazione mediante reattivi supportati e riscaldamento a microonde di esteri alpha-beta-insaturi, intermedi chiave per la sintesi di nuovi ligandi sigma 137
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 137
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 136
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 136
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 136
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 135
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 135
Electrospun alginate-PEO fibers for the delivery of sigma-1 receptor agonists in the treatment of SCI: influence of PEO molecular weight on fiber production. 135
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 134
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 134
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 134
Chiral arylpyrrolidinols: preparation and biological profile 133
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 133
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 132
Synthesis and antinociceptive activity of Pyrrolidinylnaphthalenes 132
Highly diastereoselective synthesis of enantiopure naphthylaminoalcohols with analgesic properties 132
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition 132
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 131
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 131
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? 130
Efficient Microwave and Phosphane-free Synthesis of Trisubstituted Olefins via Heck Coupling 130
Pistagremic acid, a glucosidase inhibitor from Pistacia integerrima 130
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 130
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 130
Nature aided drug discovery. Novel Compounds against Leishmaniasis from Eremurus persicus. 130
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 129
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 128
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 128
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 127
Are sigma receptor modulators a weapon against multiple sclerosis disease? 127
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 126
Synthesis of pyrrolinylnaphthalenes and evaluation of their antinociceptive activity 126
A versatile strategy for the synthesis of 4,5-dihydroxy-2,3-pentanedione (DPD) and related compounds as potential modulators of bacterial quorum sensing 126
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 126
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain 125
A practical synthesis of (3-(phenanthren-9-yl)-4,5-dihydroisoxazol-5-yl)methyl (tert-butoxycarbonyl)-L-alaninate 125
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 125
A novel composite nanosystem as a potential tool for the local treatment of glioblastoma. 124
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 124
Influence of in Vitro Simulated Gastroduodenal Digestion on Methylglyoxal Concentration of Manuka ( Lectospermum scoparium ) Honey. 124
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 124
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 123
Chiral recognition of alkyl 2-aryloxypropionates by HPLC 123
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 122
Antibacterial activity and metabolite profiling of manuka honey (Lectospermum scoparium L.) submitted to in vitro simulated digestion. 122
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 122
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 122
Synthesis and SAR of Novel Sigma1 Selective Ligands 121
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 121
From nature a new compound against Leishmania infantum 121
Risoluzione di ligandi selettivi sigma1 a struttura alchilamminoalchilarilica mediante HPLC chirale e studio configurazionale 120
Totale 14.406
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Categoria #
all - tutte 125.050
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 125.050
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.047 0 0 0 0 17 36 26 76 62 45 154 631
2022/20233.922 365 345 51 273 365 410 3 207 1.714 23 111 55
2023/20241.788 209 291 52 96 152 415 106 133 9 75 124 126
2024/20254.570 106 347 126 143 195 299 262 241 1.143 162 500 1.046
2025/202610.648 847 740 1.405 1.249 1.424 473 1.876 472 903 728 274 257
2026/20272.988 190 700 658 1.332 108 0 0 0 0 0 0 0
Totale 31.146