IRIS
COLLINA, SIMONA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 8.987
AS - Asia 6.783
EU - Europa 6.328
SA - Sud America 1.028
AF - Africa 113
Continente sconosciuto - Info sul continente non disponibili 11
OC - Oceania 1
Totale 23.251
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 8.728
CN - Cina 3.693
IE - Irlanda 1.505
SG - Singapore 1.411
IT - Italia 868
BR - Brasile 845
RU - Federazione Russa 815
HK - Hong Kong 741
DE - Germania 702
UA - Ucraina 647
FI - Finlandia 589
GB - Regno Unito 350
VN - Vietnam 338
SE - Svezia 257
FR - Francia 223
IN - India 176
CA - Canada 151
JP - Giappone 91
AR - Argentina 77
BE - Belgio 76
MX - Messico 75
PL - Polonia 59
IQ - Iraq 57
ZA - Sudafrica 52
ES - Italia 51
BD - Bangladesh 47
EC - Ecuador 31
NL - Olanda 31
TR - Turchia 31
ID - Indonesia 29
LT - Lituania 29
AT - Austria 27
CZ - Repubblica Ceca 22
VE - Venezuela 21
CO - Colombia 18
IR - Iran 18
AE - Emirati Arabi Uniti 14
CH - Svizzera 14
KR - Corea 14
PT - Portogallo 14
MA - Marocco 13
PK - Pakistan 13
EG - Egitto 11
JO - Giordania 11
PH - Filippine 11
PY - Paraguay 11
UZ - Uzbekistan 10
SA - Arabia Saudita 9
AZ - Azerbaigian 8
CL - Cile 8
EU - Europa 8
KZ - Kazakistan 8
PE - Perù 8
UY - Uruguay 8
IL - Israele 7
DK - Danimarca 6
DO - Repubblica Dominicana 6
DZ - Algeria 6
JM - Giamaica 6
NP - Nepal 6
AM - Armenia 5
GR - Grecia 5
HU - Ungheria 5
KE - Kenya 5
KG - Kirghizistan 5
LV - Lettonia 5
MU - Mauritius 5
PA - Panama 5
RO - Romania 5
TT - Trinidad e Tobago 5
AL - Albania 4
CI - Costa d'Avorio 4
HN - Honduras 4
NO - Norvegia 4
OM - Oman 4
TL - Timor Orientale 4
TN - Tunisia 4
BG - Bulgaria 3
EE - Estonia 3
LB - Libano 3
LK - Sri Lanka 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BY - Bielorussia 2
CR - Costa Rica 2
CU - Cuba 2
GA - Gabon 2
HR - Croazia 2
LA - Repubblica Popolare Democratica del Laos 2
MN - Mongolia 2
MY - Malesia 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
TW - Taiwan 2
AO - Angola 1
AU - Australia 1
BH - Bahrain 1
BJ - Benin 1
BO - Bolivia 1
CG - Congo 1
Totale 23.234
Salva come PNG Salva come JPEG
Città #
Dublin 1.502
Chandler 1.365
Dallas 949
Beijing 831
Jacksonville 788
Ashburn 743
Nanjing 735
Hong Kong 733
Singapore 714
Boardman 406
Ann Arbor 288
Los Angeles 282
Nanchang 269
Princeton 237
Lawrence 226
New York 219
Munich 217
Helsinki 216
Hebei 214
Shenyang 196
Shanghai 193
Wilmington 185
Pavia 182
Changsha 173
Medford 173
Jiaxing 157
Moscow 149
Ho Chi Minh City 140
Tianjin 128
Hangzhou 122
Milan 122
Redondo Beach 120
Buffalo 98
Tokyo 84
São Paulo 79
Pune 78
Brussels 72
Toronto 69
Woodbridge 68
Turku 66
Seattle 60
Hanoi 56
The Dalles 55
Warsaw 52
Orem 49
Santa Clara 48
Chennai 44
Piscataway 43
Norwalk 42
Stockholm 42
Chicago 41
Denver 40
Johannesburg 40
London 36
Montreal 35
Rio de Janeiro 32
Columbus 31
Houston 31
Brooklyn 30
Poplar 30
Mexico City 29
Dearborn 28
Verona 28
Atlanta 27
Guangzhou 27
Fairfield 25
Falkenstein 25
Florence 25
Frankfurt am Main 25
Phoenix 25
San Francisco 24
Boston 23
Manchester 23
Zhengzhou 23
Des Moines 22
Washington 22
Nuremberg 21
Haiphong 20
Sulaymaniyah 20
Rome 18
Da Nang 17
Jinan 17
Mountain View 17
Amsterdam 16
Auburn Hills 16
Redwood City 16
San Jose 16
Brasília 15
Council Bluffs 15
Curitiba 15
Belo Horizonte 14
Ottawa 14
Campinas 13
Naples 13
Quito 13
Baghdad 12
Bologna 12
Seoul 12
Amman 11
Ankara 11
Totale 15.190
Salva come PNG Salva come JPEG
Nome #
Estrazione mediante microonde (MASE) di cumarina e composti correlati da Melilotus officinalis, una valida alternativa all'estrazione con Soxhlet e con ultrasuoni (USAE). 405
Quantitative evaluation of RC-106 antitumor activity in GBM spheroids through tumor growth inhibition modeling based on cell counts data 156
Estrazione di flavonoidi da Crataegus monogyna Jacq. mediante microonde (MASE), un'alternativa alla macerazione, all'estrazione con Soxhlet e con ultrasuoni (USAE). 150
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 148
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 139
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 139
Disegno razionale e sintesi di ligandi selettivi per il sottotipo recettoriale sigma1 138
Microwave assisted synthesis of chiral pyrrolines with biological activity 135
Approaches for multi-gram scale isolation of enantiomers for drug discovery 135
A composite nanosystem as a potential tool for the local treatment of glioblastoma: Chitosan‐coated solid lipid nanoparticles embedded in electrospun nanofibers 135
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 133
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 133
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 133
Formulation of microspheres containing Crataegus monogyna extract in feed design 131
ASSESMENT OF MARRUBIUM VULGARE L. HERBAL RAW MATERIAL QUALITY. SET UP OF A COMBINED MASE AND HPLC-UV/PAD METHODOLOGY DRIVEN BY DOE 131
SAR Evaluation of Chiral Naphthylorfines with Antinociceptive Activity 130
Disegno razionale, sintesi e valutazione biologica di nuovi ligandi ad elevata affinità per i recettori sigma 1 a struttura fenilalchenil- e fenilalchil- amminica 129
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 127
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 125
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 125
Progettazione e Sintesi di nuovi Ligandi Sigma 124
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 124
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 123
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 123
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 123
Sintesi parallela in soluzione di scaffolds olefinici per la preparazione di nuovi ligandi sigma 122
Preparazione mediante reattivi supportati e riscaldamento a microonde di esteri alpha-beta-insaturi, intermedi chiave per la sintesi di nuovi ligandi sigma 122
Novel sigma ligands: design, preparation and biological evaluation 121
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 121
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 120
Alginate-based electrospun fibers for the delivery of sigma-1 receptor agonists in the treatment of spinal cord injuries 119
Sigma receptor modulators: a patent review. 118
Preparation and Configuration of Racemic and Optically Active Analgesic Cycloaminoalkiynaphthalenes 117
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 117
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 117
Estrazione di cumarina da Melilotus officinalis (L.) Pallas. 116
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 116
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 116
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 115
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 115
Dialkylaminoalkylnaphthalenes as novel opioid-like analgesics 114
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 114
Synthesis of pyrrolinylnaphthalenes and evaluation of their antinociceptive activity 114
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 114
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 113
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 113
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 111
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 111
Nature inspired new compounds against Leishmaniosis, from Eremurus persicus 111
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 110
Pistagremic acid, a glucosidase inhibitor from Pistacia integerrima 110
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 110
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 110
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 110
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 109
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 109
Design, synthesis and pharmacological activity of new antinociceptive agents 108
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 107
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 107
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 107
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 106
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition 106
Derivati indolilalchilaminici. Approccio razionale alla progettazione di nuovi ligandi sigma 105
Chiral recognition of alkyl 2-aryloxypropionates by HPLC 105
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 105
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 105
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 104
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 104
DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance 104
Synthesis and SAR of Novel Sigma1 Selective Ligands 103
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 103
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 103
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 103
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 103
Antibacterial activity and metabolite profiling of manuka honey (Lectospermum scoparium L.) submitted to in vitro simulated digestion. 102
Risoluzione di ligandi selettivi sigma1 a struttura alchilamminoalchilarilica mediante HPLC chirale e studio configurazionale 102
Chiral arylpyrrolidinols: preparation and biological profile 102
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 102
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 102
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 102
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? 101
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 101
A practical synthesis of (3-(phenanthren-9-yl)-4,5-dihydroisoxazol-5-yl)methyl (tert-butoxycarbonyl)-L-alaninate 100
Electrospun alginate-PEO fibers for the delivery of sigma-1 receptor agonists in the treatment of SCI: influence of PEO molecular weight on fiber production. 100
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 99
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 99
DRUG DISCOVERY FROM PLANTS: TRADITIONAL HERBAL REMEDIES AS SOURCE FOR NEW LEAD COMPOUNDS 98
Highly diastereoselective synthesis of enantiopure naphthylaminoalcohols with analgesic properties 98
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 98
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 97
Diastereoselective synthesis of chiral nonracemic naphthylaminoalcohols with analgesic activity 97
Development of a mucoadhesive and an in situ gelling formulation based on κ-carrageenan for application on oral mucosa and esophagus walls. II. Loading of a bioactive hydroalcoholic extract 97
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain 96
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 96
Chiral resolution and absolute configuration of the enantiomers of 5-acetyl-2-methyl-4-methylsulfinyl-6-phenyl-3(2H)-pyridazinone and evaluation of their platelet aggregationinhibitory activity 96
Pharmacophore-based drug design of novel selective sigma1 ligands 95
Nature aided drug discovery. Novel Compounds against Leishmaniasis from Eremurus persicus. 95
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 94
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 94
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target 94
Totale 11.594
Salva come PNG Salva come JPEG
Categoria #
all - tutte 96.594
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 96.594
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021885 0 0 0 0 0 183 31 207 59 199 162 44
2021/20221.153 20 16 51 19 17 36 26 76 62 45 154 631
2022/20233.922 365 345 51 273 365 410 3 207 1.714 23 111 55
2023/20241.788 209 291 52 96 152 415 106 133 9 75 124 126
2024/20254.570 106 347 126 143 195 299 262 241 1.143 162 500 1.046
2025/20266.126 847 740 1.405 1.249 1.424 461 0 0 0 0 0 0
Totale 23.636