IRIS
COLLINA, SIMONA
 Distribuzione geografica
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Continente #
NA - Nord America 5.886
EU - Europa 4.617
AS - Asia 3.241
SA - Sud America 24
AF - Africa 10
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 1
Totale 13.789
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Nazione #
US - Stati Uniti d'America 5.805
CN - Cina 2.692
IE - Irlanda 1.503
IT - Italia 716
UA - Ucraina 628
FI - Finlandia 517
DE - Germania 479
SG - Singapore 367
SE - Svezia 215
GB - Regno Unito 207
FR - Francia 190
IN - India 89
CA - Canada 75
BE - Belgio 74
JP - Giappone 27
IQ - Iraq 21
RU - Federazione Russa 16
LT - Lituania 15
BR - Brasile 14
IR - Iran 13
PT - Portogallo 12
CZ - Repubblica Ceca 9
HK - Hong Kong 9
CH - Svizzera 8
EU - Europa 8
NL - Olanda 8
MU - Mauritius 5
ES - Italia 4
GR - Grecia 3
MA - Marocco 3
PK - Pakistan 3
TL - Timor Orientale 3
TR - Turchia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AR - Argentina 2
AT - Austria 2
BD - Bangladesh 2
CL - Cile 2
CO - Colombia 2
CU - Cuba 2
DK - Danimarca 2
DZ - Algeria 2
ID - Indonesia 2
KR - Corea 2
LV - Lettonia 2
MX - Messico 2
PH - Filippine 2
PL - Polonia 2
RO - Romania 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
AU - Australia 1
BG - Bulgaria 1
BO - Bolivia 1
DO - Repubblica Dominicana 1
EC - Ecuador 1
HR - Croazia 1
HU - Ungheria 1
IL - Israele 1
LA - Repubblica Popolare Democratica del Laos 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PY - Paraguay 1
TW - Taiwan 1
Totale 13.789
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Città #
Dublin 1.500
Chandler 1.365
Jacksonville 786
Nanjing 732
Ashburn 417
Boardman 405
Beijing 364
Ann Arbor 288
Singapore 280
Nanchang 269
Princeton 237
Lawrence 226
Hebei 214
Helsinki 211
Shenyang 194
Wilmington 185
Shanghai 182
Medford 173
Pavia 165
Changsha 163
Jiaxing 157
Tianjin 124
Hangzhou 118
New York 116
Milan 96
Pune 75
Brussels 70
Woodbridge 68
Munich 62
Toronto 56
Seattle 52
Los Angeles 47
Piscataway 43
Norwalk 42
Dearborn 28
Tokyo 27
Verona 26
Fairfield 25
Des Moines 22
Sulaymaniyah 20
Washington 20
Dallas 19
Mountain View 17
Auburn Hills 16
Redwood City 16
Frankfurt am Main 14
Ottawa 14
Guangzhou 13
Jinan 13
London 13
Zhengzhou 13
Bologna 12
Florence 11
Chicago 10
Houston 10
Ningbo 10
Couilly-pont-aux-dames 9
Kunming 9
Rome 9
Brno 8
Falkenstein 8
Trezzano Rosa 8
Changchun 7
Paris 7
Pisa 7
Siena 7
Fuzhou 6
Guimarães 6
Hong Kong 6
Orange 6
Aachen 5
Braga 5
Falls Church 5
Girifalco 5
Padova 5
Torino 5
Turin 5
Andover 4
Berlin 4
Caleppio 4
Chennai 4
Guiyang 4
Moscow 4
Nagold 4
Redmond 4
Rennes 4
Salerno 4
San Francisco 4
Santa Clara 4
Taizhou 4
Tappahannock 4
Wetter 4
Ancona 3
Angri 3
Borås 3
Bresso 3
Calderara Di Reno 3
Campina Grande 3
Castrovillari 3
Cornate d'Adda 3
Totale 10.073
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Nome #
Estrazione mediante microonde (MASE) di cumarina e composti correlati da Melilotus officinalis, una valida alternativa all'estrazione con Soxhlet e con ultrasuoni (USAE). 352
Estrazione di flavonoidi da Crataegus monogyna Jacq. mediante microonde (MASE), un'alternativa alla macerazione, all'estrazione con Soxhlet e con ultrasuoni (USAE). 123
Disegno razionale e sintesi di ligandi selettivi per il sottotipo recettoriale sigma1 100
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 99
Formulation of microspheres containing Crataegus monogyna extract in feed design 98
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 97
Disegno razionale, sintesi e valutazione biologica di nuovi ligandi ad elevata affinità per i recettori sigma 1 a struttura fenilalchenil- e fenilalchil- amminica 96
SAR Evaluation of Chiral Naphthylorfines with Antinociceptive Activity 95
Estrazione di cumarina da Melilotus officinalis (L.) Pallas. 93
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 92
Sintesi parallela in soluzione di scaffolds olefinici per la preparazione di nuovi ligandi sigma 91
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 91
Preparazione mediante reattivi supportati e riscaldamento a microonde di esteri alpha-beta-insaturi, intermedi chiave per la sintesi di nuovi ligandi sigma 90
Pistagremic acid, a glucosidase inhibitor from Pistacia integerrima 89
Preparation and Configuration of Racemic and Optically Active Analgesic Cycloaminoalkiynaphthalenes 88
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 88
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 88
Progettazione e Sintesi di nuovi Ligandi Sigma 87
Antibacterial activity and metabolite profiling of manuka honey (Lectospermum scoparium L.) submitted to in vitro simulated digestion. 86
Microwave assisted synthesis of chiral pyrrolines with biological activity 86
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 84
Dialkylaminoalkylnaphthalenes as novel opioid-like analgesics 83
Synthesis of pyrrolinylnaphthalenes and evaluation of their antinociceptive activity 82
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 82
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 81
Novel sigma ligands: design, preparation and biological evaluation 81
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 81
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 81
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 80
Sigma receptor modulators: a patent review. 80
Synthesis and SAR of Novel Sigma1 Selective Ligands 79
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 79
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 79
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 79
Design, synthesis and pharmacological activity of new antinociceptive agents 77
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 77
ASSESMENT OF MARRUBIUM VULGARE L. HERBAL RAW MATERIAL QUALITY. SET UP OF A COMBINED MASE AND HPLC-UV/PAD METHODOLOGY DRIVEN BY DOE 77
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 76
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 76
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 75
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 75
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 75
Chiral recognition of alkyl 2-aryloxypropionates by HPLC 75
Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 75
Derivati indolilalchilaminici. Approccio razionale alla progettazione di nuovi ligandi sigma 74
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 74
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 74
Approaches for multi-gram scale isolation of enantiomers for drug discovery 74
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 73
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target 73
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 73
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 73
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 72
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 72
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 72
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 72
Nature inspired new compounds against Leishmaniosis, from Eremurus persicus 71
Benzooxazol-2-one and benzothiazol-2-one derivatives as possibile sigma ligands 70
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 70
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 70
Risoluzione di ligandi selettivi sigma1 a struttura alchilamminoalchilarilica mediante HPLC chirale e studio configurazionale 69
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 69
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 69
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 69
Microwave Assisted Synthesis of Chiral Pyrrolinyl-Naphthalenes and evaluation of their Antinociceptive Activity 68
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 68
Pharmacophore-based drug design of novel selective sigma1 ligands 67
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 67
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 67
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 67
Synthesis and pharmacological evaluation of opiod-like chiral naphthylaminoalcohols 67
Rational Approach to the Design of Selective Sigma 1 Ligands 66
Binding Studies and Quantitative Structure-Activity Relationship of 3-Amino-1H-Indazoles as Inhibitors of GSK3beta 66
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 66
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 66
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 66
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 66
Chiral resolution and absolute configuration of the enantiomers of 5-acetyl-2-methyl-4-methylsulfinyl-6-phenyl-3(2H)-pyridazinone and evaluation of their platelet aggregationinhibitory activity 66
Efficient Microwave and Phosphane-free Synthesis of Trisubstituted Olefins via Heck Coupling 65
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 65
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 65
Chiral arylpyrrolidinols: preparation and biological profile 64
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 64
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 64
DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance 64
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 64
A composite nanosystem as a potential tool for the local treatment of glioblastoma: Chitosan‐coated solid lipid nanoparticles embedded in electrospun nanofibers 63
Preliminary study on TNF alpha-blocker activity of Amygdalus lycioides Spach extracts 62
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 62
Microwave-assisted extraction of coumarin and related compounds from Melilotus officinalis (L.) Pallas as an alternative to Soxhlet and ultrasound-assisted extraction 62
Nature aided drug discovery. Novel Compounds against Leishmaniasis from Eremurus persicus. 62
Microspheres containing an extract of Crataegus monogyna Jacq. for oral administration. 61
Proteometric study of ghrelin receptor function variations upon mutations using amino acid sequence autocorrelation vectors and genetic algorithm-based least square support vector machines 61
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells. 61
Synthesis and antinociceptive activity of Pyrrolidinylnaphthalenes 61
Highly diastereoselective synthesis of enantiopure naphthylaminoalcohols with analgesic properties 61
New Perspectives in Lithium Carbenoid Mediated Homologations 61
Synthesis and biological evaluation of small peptides able to mimic ELAV RNA-binding proteins: new perspective in neurodegenerative diseases treatment 60
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 60
Electrospun alginate-PEO fibers for the delivery of sigma-1 receptor agonists in the treatment of SCI: influence of PEO molecular weight on fiber production. 60
Totale 7.756
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Categoria #
all - tutte 58.517
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.517
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020852 0 0 0 0 0 129 34 160 39 274 205 11
2020/20211.342 147 116 32 139 23 183 31 207 59 199 162 44
2021/20221.153 20 16 51 19 17 36 26 76 62 45 154 631
2022/20233.922 365 345 51 273 365 410 3 207 1.714 23 111 55
2023/20241.788 209 291 52 96 152 415 106 133 9 75 124 126
2024/20251.207 106 347 126 143 196 289 0 0 0 0 0 0
Totale 14.147