IRIS
CURTI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 3.887
AS - Asia 2.995
EU - Europa 2.614
SA - Sud America 403
AF - Africa 74
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 9.979
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Nazione #
US - Stati Uniti d'America 3.810
CN - Cina 1.611
SG - Singapore 579
IE - Irlanda 542
UA - Ucraina 372
DE - Germania 313
HK - Hong Kong 305
FI - Finlandia 304
BR - Brasile 300
RU - Federazione Russa 268
IT - Italia 217
VN - Vietnam 212
FR - Francia 183
SE - Svezia 158
GB - Regno Unito 149
IN - India 87
CA - Canada 42
ZA - Sudafrica 40
AR - Argentina 39
BD - Bangladesh 31
IQ - Iraq 24
BE - Belgio 21
JP - Giappone 20
MX - Messico 19
ID - Indonesia 18
EC - Ecuador 17
ES - Italia 17
CO - Colombia 16
PL - Polonia 14
TR - Turchia 14
PH - Filippine 13
PK - Pakistan 13
NL - Olanda 11
SA - Arabia Saudita 11
VE - Venezuela 10
LT - Lituania 9
MA - Marocco 9
UZ - Uzbekistan 9
MY - Malesia 6
CL - Cile 5
KE - Kenya 5
PE - Perù 5
PY - Paraguay 5
AT - Austria 4
CZ - Repubblica Ceca 4
EG - Egitto 4
IL - Israele 4
JM - Giamaica 4
KZ - Kazakistan 4
TN - Tunisia 4
AU - Australia 3
AZ - Azerbaigian 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
IR - Iran 3
KG - Kirghizistan 3
KR - Corea 3
LU - Lussemburgo 3
MU - Mauritius 3
NI - Nicaragua 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
BO - Bolivia 2
BY - Bielorussia 2
CG - Congo 2
CH - Svizzera 2
DZ - Algeria 2
EE - Estonia 2
ET - Etiopia 2
GE - Georgia 2
GY - Guiana 2
JO - Giordania 2
KH - Cambogia 2
LV - Lettonia 2
PA - Panama 2
PT - Portogallo 2
RO - Romania 2
RS - Serbia 2
SY - Repubblica araba siriana 2
UY - Uruguay 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
CI - Costa d'Avorio 1
CY - Cipro 1
EU - Europa 1
GI - Gibilterra 1
GR - Grecia 1
HR - Croazia 1
HU - Ungheria 1
KW - Kuwait 1
LB - Libano 1
LC - Santa Lucia 1
LK - Sri Lanka 1
ML - Mali 1
MN - Mongolia 1
MZ - Mozambico 1
NP - Nepal 1
Totale 9.971
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Città #
Chandler 570
Dublin 542
Jacksonville 444
Nanjing 371
San Jose 346
Ashburn 330
Singapore 308
Beijing 307
Hong Kong 300
Dallas 217
Boardman 170
Nanchang 137
Los Angeles 109
Princeton 105
Lawrence 104
Hebei 98
Shenyang 97
Helsinki 96
Lauterbourg 94
Changsha 92
Jiaxing 87
Munich 86
Medford 79
Wilmington 79
Ann Arbor 75
Ho Chi Minh City 72
New York 62
Pavia 57
Buffalo 54
Milan 54
Tianjin 54
Hanoi 49
Shanghai 49
Moscow 48
Hangzhou 45
São Paulo 44
Orem 33
Johannesburg 32
Piscataway 31
Verona 30
Woodbridge 27
Redondo Beach 23
Toronto 20
The Dalles 19
Tokyo 19
Chennai 18
Norwalk 18
Turku 18
Brussels 17
Santa Clara 17
Seattle 17
Pune 16
Montreal 15
Stockholm 15
Chicago 14
Houston 13
Haiphong 12
London 12
Warsaw 12
Denver 11
Falkenstein 11
Frankfurt am Main 11
San Francisco 11
Atlanta 10
Brooklyn 10
Columbus 10
Curitiba 10
Poplar 10
Rome 10
Boston 9
Da Nang 9
Falls Church 9
Guangzhou 9
Mumbai 9
Rio de Janeiro 9
Tashkent 9
Amsterdam 8
Baghdad 8
Basingstoke 8
Brasília 8
Couilly-pont-aux-dames 8
Jinan 8
Manchester 8
Mexico City 8
Fairfield 7
Hải Dương 7
Phoenix 7
Zhengzhou 7
Ankara 6
Auburn Hills 6
Jakarta 6
Kunming 6
Quito 6
Shijiazhuang 6
Washington 6
Campinas 5
Des Moines 5
Duque de Caxias 5
Jeddah 5
Lima 5
Totale 6.605
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Nome #
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 157
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 145
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 143
SOD1 activity and protective factors in familial ALS patients with L84F SOD1 mutation 143
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 142
Analysis of the early mitochondrial damage in G93A-SOD1 transgenic mice (SOD1-TG) 141
Clustering of ALS patients in central Italy due to the occurrence of the L84F SOD1 gene mutation 138
A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells. 138
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 137
Age-dependent modification of drug interference on the enzymatic activities of the rat brain 135
Age-related acute depletion of cerebral glutathione by peroxidative stress 129
Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes 127
Early effects of AZT on mitochondrial functions in the absence of mitochondrial DNA depletetion in rat myotubes 125
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 125
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 124
Age-related modification of enzyme activities in synaptosomes isolated from rat cerebral cortex 120
Modified expression of Bcl-2 and SOD1 proteins in lymphocytes from sporadic ALS patients 120
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 120
SOD1 activity and protective factors in familial ALS patients with L84F SOD1 mutation 118
Brain enzyme adaptation to mild normobaric intermittent hypoxia 118
Mitochondrial oxidative metabolism in motor neuron degeneration (mnd) mouse central nervous system 117
Effect of ischemia and pharmacological treatment on subcellular from neonatal rat brain 117
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 116
Apoptosis or necrosis in motoneurons: intracellular responses to excitotoxic insults 114
Effect of hypoxia on brain energy metabolism during aging 113
Are sigma receptor modulators a weapon against multiple sclerosis disease? 113
Basic and clinical research on amyotrophic lateral sclerosis and other motor neuron disorders in Italy: recent findings and achievements from a network of laboratories 112
Astrocytes derived from neural precursor cells of wobbler mice induce apoptotic death of motor neurons through reduced glutamate transport 110
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 109
Effect of hypoxia and pharmacological treatment on some enzyme activities in dog brain areas 109
Heterogeneous distribution of amyotrophic lateral sclerosis patient with SOD-1 gene mulations: preliminary data on an Italian survey 107
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 107
Effect of vincamine on some enzymatic activities from various areas of the beagle dog cerebral cortex 107
Alteration of complex IV and acethylcholine-related enzymes in experimental spinal cord injury 106
Effect of prolonged and intermittent hypoxia on some cerebral enzymatic activities related to energy transduction 105
Dose/action and time/action relationships of some biological molecules evaluated on the cerebral enzymatic activities 105
Alteration of pallidal cholinergic activity in MPTP-treated monkeys: effect of dihydro-alpha-ergocryptine (DEK) 105
Effect of Ca2+-homopantothenate and mild hypoxia on some enzyme activities evaluated in subcellular fractions from different rat brain regions 105
Influence of intermittent hypoxia and pyrimidinic nucleosides on cerebral enzymatic activities related to energy transduction 104
Amyotrophic lateral sclerosis and SOD1 gene: an overview 104
Kinetics of irreversible inhibition of choline transport in synaptosomes by ethylcholine mustard aziridinium 103
Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients 103
Effect of aging and acetyl-L-carnitine on energetic and cholinergic metabolism in rat brain regions 103
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 101
Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells 100
Age-related modifications of cytochrome C oxidase activity in discrete brain regions 100
Drug interference on the age-dependent modification of the cerebral enzymatic activities related to energy transduction 100
Cerebral enzymatic activities during chronic hyperammonemia and treatment with S-adenosyl-L-methionine, adenosine and methionine in the rat 99
Characterisation of adult neural stem cells from wobbler motor neuron disease mice 99
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 99
S-Adenosyl-L-methionine, related compounds, and cerebral enzymatic activities during chronic hyperammonemia in rats 97
Sequential damage in mitochondrial complexes by peroxidative stress 97
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 97
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 96
Modified expression of antioxidant enzymes in lymphocytes of sporadic amyotrophic lateral sclerosis patients 95
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 93
Endothelin B receptor antagonists block proliferation and induce apoptosis in glioma cells 93
Enzymes related to energy metabolism in human gliomas 92
Les modifications enzymatiques du cerveau age chez le rat 91
Effect of chronic treatment with some drugs on the enzymatic activities of the rat brain 91
Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake 90
Mitochondrial dysfunction in a murine model of motor neuron disease 88
Synaptosomes and mitochondria from rat brain cerebral cortex: in vivo interference on some enzymatic activities by SAMe and CDP-choline 88
Mitochondrial alterations in asymptomatic G93A-SOD1 transgenic mice (SOD1-TG) 87
Chemical, pharmacological and in vivo pharmacokinetic studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists 87
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain 86
Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease 86
The mitochondrial electron transfer alteration as a factor involved in the brain aging 86
Role of cerebral enzymatic activities in the relationships between energy metabolism and amino acid acting as neurotrasmitters 85
Heterogeneous distribution of amyotrophic lateral sclerosis patients with SOD-1 gene mutations: preliminary data on an Italian survey. 85
Use of arylalkanolamines as sigma-1 receptor antagonists 84
Rapid flow cytometric assessment of cell membrane integrity by Hoechst 33342 and Propidium Iodide labeling 81
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084,in a mouse model of motor neuron disease not linked to SOD1 mutation 81
Mitochondrial function in lymphocytes from sporadic ALS and familial ALS patients 81
Energy metabolism inhibition impairs amyloid precursor protein secretion from Alzheimer's fibroblasts 80
Studies on the enantiomers of RC-33, promising neuroprotective agents acting as sigma1 receptor agonists. Isolation, configurational assignment and biological profile 80
Towards the identification of neuroprotective agents. Pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising sigma1 receptor agonist 80
Early alterations of mitochondrial function and morphology in the cervical spinal cord of the wobbler mouse 78
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 78
Phenobarbital and 6-aminonicotinamide effect on cerebral enzymatic activities related to energy metabolism in different rat brain areas 75
Toward the identification of neuroprotective agents: G-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist 75
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 74
Mitochondrial involvement in schizophrenia and other functional psychoses 74
Sigma receptors as endoplasmic reticulum stress "gatekeepers" and their modulators as emerging new weapons in the fight against cancer 74
Influence of age upon the cerebral metabolic changes induced by acute hypoxia on the synaptosomes from dog brain 72
Implication of the antioxidant pathway in lymphocytes of sporadic amyotrophic lateral sclerosis patients 70
Modification produced by ischemia on some cerebral enzyme activities related to energy transduction 70
Sigma1 Receptor Agonists in motor dysfunction pathologies treatment – a medicinal chemistry perspective 70
Effect of a ubiquinone-like molecule on oxidative energy metabolism in rat cortical synaptosomes at different ages 70
Neural precursors (NPCs) from adult L967Q mice display early commitment to "in vitro" neuronal differentiation and hyperexcitability 68
Mitochondrial energy metabolism is preserved in the lumbar spinal cord of the wobbler mouse 67
Erythropoietin protects primary motor neuron cultures from apoptotic but not necrotic death in vitro 67
Proteomic profiling of cervical and lumbar spinal cord reveals potential protective mechanisms in the wobbler mouse, a model of motor neuron degeneration. 66
Effects of ionotropic glutamate receptor stimulation and mitochondrial inhibition in rat spinal cord motor neurons 65
The effect of ischemia and pharmacological treatment evaluated on synaptosomes and purified mitochondria from rat cerebral cortex 65
Oxidative metabolism of non-synaptic mitochondria isolated from rat brain hippocampus: a comparative regional study 64
Do lymphocytes from sporadic ALS patients show disease traits ? 60
Superoxide, neuroleptics and ubiquinone and cytochrome b5 reductases in brain and lymphocytes from normals and schizophrenic patients 59
Influence of aging on the acute depletion of reduced glutathione induced by electrophilic agents 58
Role of synaptosomal enzymatic alterations and drug treatment in brain aging 57
Totale 9.790
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Categoria #
all - tutte 39.357
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.357
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021219 0 0 0 0 0 0 0 0 0 104 90 25
2021/2022460 7 1 11 8 6 21 10 23 27 15 65 266
2022/20231.589 179 137 5 138 175 166 2 80 648 3 36 20
2023/2024534 85 83 10 33 49 133 13 44 4 19 50 11
2024/20251.437 23 118 45 48 55 70 40 98 354 43 168 375
2025/20263.117 273 262 410 344 373 170 651 123 326 185 0 0
Totale 10.048