IRIS
CURTI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 3.301
AS - Asia 2.474
EU - Europa 2.428
SA - Sud America 319
AF - Africa 30
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.557
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Nazione #
US - Stati Uniti d'America 3.248
CN - Cina 1.552
IE - Irlanda 542
SG - Singapore 446
UA - Ucraina 370
DE - Germania 305
FI - Finlandia 301
HK - Hong Kong 265
RU - Federazione Russa 262
BR - Brasile 261
IT - Italia 207
SE - Svezia 155
GB - Regno Unito 122
VN - Vietnam 91
FR - Francia 83
IN - India 39
CA - Canada 31
AR - Argentina 25
BE - Belgio 21
ZA - Sudafrica 14
JP - Giappone 13
ID - Indonesia 12
MX - Messico 12
EC - Ecuador 11
BD - Bangladesh 9
PL - Polonia 9
ES - Italia 8
IQ - Iraq 8
LT - Lituania 8
NL - Olanda 7
TR - Turchia 7
CO - Colombia 6
VE - Venezuela 5
AT - Austria 4
IL - Israele 4
MA - Marocco 4
PY - Paraguay 4
UZ - Uzbekistan 4
AU - Australia 3
CL - Cile 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
KG - Kirghizistan 3
KR - Corea 3
LU - Lussemburgo 3
MU - Mauritius 3
PK - Pakistan 3
BY - Bielorussia 2
CG - Congo 2
DO - Repubblica Dominicana 2
EE - Estonia 2
IR - Iran 2
JM - Giamaica 2
KZ - Kazakistan 2
LV - Lettonia 2
NI - Nicaragua 2
PE - Perù 2
PH - Filippine 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
CH - Svizzera 1
CI - Costa d'Avorio 1
CY - Cipro 1
DZ - Algeria 1
EG - Egitto 1
EU - Europa 1
GI - Gibilterra 1
GR - Grecia 1
GY - Guiana 1
HU - Ungheria 1
KE - Kenya 1
LB - Libano 1
LC - Santa Lucia 1
LK - Sri Lanka 1
ML - Mali 1
MY - Malesia 1
MZ - Mozambico 1
NZ - Nuova Zelanda 1
PA - Panama 1
PR - Porto Rico 1
PT - Portogallo 1
RS - Serbia 1
SA - Arabia Saudita 1
TH - Thailandia 1
TN - Tunisia 1
UY - Uruguay 1
Totale 8.557
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Città #
Chandler 570
Dublin 542
Jacksonville 444
Nanjing 371
Beijing 300
Hong Kong 265
Ashburn 246
Dallas 216
Singapore 211
Boardman 170
Nanchang 137
Princeton 105
Lawrence 104
Hebei 98
Los Angeles 97
Shenyang 97
Helsinki 93
Changsha 92
Jiaxing 87
Munich 86
Medford 79
Wilmington 79
Ann Arbor 75
New York 59
Pavia 57
Milan 54
Tianjin 54
Buffalo 51
Shanghai 49
Moscow 48
Hangzhou 45
São Paulo 38
Ho Chi Minh City 32
Piscataway 31
Verona 30
Woodbridge 27
Redondo Beach 23
Hanoi 19
The Dalles 19
Norwalk 18
Turku 18
Brussels 17
Seattle 17
Toronto 17
Pune 15
Chicago 13
Houston 13
Tokyo 13
Stockholm 12
Falkenstein 11
San Francisco 11
Santa Clara 11
Columbus 10
Orem 10
Boston 9
Curitiba 9
Denver 9
Falls Church 9
Johannesburg 9
Rio de Janeiro 9
Rome 9
Brasília 8
Couilly-pont-aux-dames 8
Jinan 8
London 8
Brooklyn 7
Chennai 7
Fairfield 7
Haiphong 7
Montreal 7
Warsaw 7
Zhengzhou 7
Auburn Hills 6
Guangzhou 6
Kunming 6
Shijiazhuang 6
Ankara 5
Atlanta 5
Manchester 5
Mexico City 5
Mumbai 5
Ningbo 5
Phoenix 5
Poplar 5
Taizhou 5
Wuhan 5
Amsterdam 4
Baghdad 4
Des Moines 4
Frankfurt am Main 4
Fuzhou 4
Guayaquil 4
Hải Dương 4
Jakarta 4
Newark 4
Padova 4
Pittsburgh 4
Porto Alegre 4
Recife 4
Redwood City 4
Totale 5.680
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Nome #
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 138
SOD1 activity and protective factors in familial ALS patients with L84F SOD1 mutation 133
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 131
A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells. 126
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 125
Clustering of ALS patients in central Italy due to the occurrence of the L84F SOD1 gene mutation 121
Analysis of the early mitochondrial damage in G93A-SOD1 transgenic mice (SOD1-TG) 120
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 120
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 119
Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes 116
Age-dependent modification of drug interference on the enzymatic activities of the rat brain 116
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 113
Age-related acute depletion of cerebral glutathione by peroxidative stress 109
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 109
Early effects of AZT on mitochondrial functions in the absence of mitochondrial DNA depletetion in rat myotubes 107
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 106
Age-related modification of enzyme activities in synaptosomes isolated from rat cerebral cortex 104
Modified expression of Bcl-2 and SOD1 proteins in lymphocytes from sporadic ALS patients 102
SOD1 activity and protective factors in familial ALS patients with L84F SOD1 mutation 102
Brain enzyme adaptation to mild normobaric intermittent hypoxia 102
Effect of ischemia and pharmacological treatment on subcellular from neonatal rat brain 99
Apoptosis or necrosis in motoneurons: intracellular responses to excitotoxic insults 99
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 98
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 97
Effect of hypoxia on brain energy metabolism during aging 97
Effect of vincamine on some enzymatic activities from various areas of the beagle dog cerebral cortex 96
Heterogeneous distribution of amyotrophic lateral sclerosis patient with SOD-1 gene mulations: preliminary data on an Italian survey 95
Mitochondrial oxidative metabolism in motor neuron degeneration (mnd) mouse central nervous system 95
Basic and clinical research on amyotrophic lateral sclerosis and other motor neuron disorders in Italy: recent findings and achievements from a network of laboratories 94
Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients 93
Are sigma receptor modulators a weapon against multiple sclerosis disease? 93
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 91
Influence of intermittent hypoxia and pyrimidinic nucleosides on cerebral enzymatic activities related to energy transduction 91
Effect of aging and acetyl-L-carnitine on energetic and cholinergic metabolism in rat brain regions 90
Amyotrophic lateral sclerosis and SOD1 gene: an overview 90
Age-related modifications of cytochrome C oxidase activity in discrete brain regions 89
Alteration of pallidal cholinergic activity in MPTP-treated monkeys: effect of dihydro-alpha-ergocryptine (DEK) 89
Kinetics of irreversible inhibition of choline transport in synaptosomes by ethylcholine mustard aziridinium 88
Characterisation of adult neural stem cells from wobbler motor neuron disease mice 88
Effect of prolonged and intermittent hypoxia on some cerebral enzymatic activities related to energy transduction 87
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 87
Alteration of complex IV and acethylcholine-related enzymes in experimental spinal cord injury 87
Effect of hypoxia and pharmacological treatment on some enzyme activities in dog brain areas 87
Cerebral enzymatic activities during chronic hyperammonemia and treatment with S-adenosyl-L-methionine, adenosine and methionine in the rat 86
Astrocytes derived from neural precursor cells of wobbler mice induce apoptotic death of motor neurons through reduced glutamate transport 86
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 86
S-Adenosyl-L-methionine, related compounds, and cerebral enzymatic activities during chronic hyperammonemia in rats 85
Dose/action and time/action relationships of some biological molecules evaluated on the cerebral enzymatic activities 85
Effect of Ca2+-homopantothenate and mild hypoxia on some enzyme activities evaluated in subcellular fractions from different rat brain regions 85
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 85
Modified expression of antioxidant enzymes in lymphocytes of sporadic amyotrophic lateral sclerosis patients 83
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 83
Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells 82
Sequential damage in mitochondrial complexes by peroxidative stress 82
Drug interference on the age-dependent modification of the cerebral enzymatic activities related to energy transduction 81
Mitochondrial dysfunction in a murine model of motor neuron disease 80
Enzymes related to energy metabolism in human gliomas 80
Endothelin B receptor antagonists block proliferation and induce apoptosis in glioma cells 79
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 78
Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake 77
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain 75
Mitochondrial alterations in asymptomatic G93A-SOD1 transgenic mice (SOD1-TG) 75
Role of cerebral enzymatic activities in the relationships between energy metabolism and amino acid acting as neurotrasmitters 75
Les modifications enzymatiques du cerveau age chez le rat 75
The mitochondrial electron transfer alteration as a factor involved in the brain aging 75
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084,in a mouse model of motor neuron disease not linked to SOD1 mutation 74
Heterogeneous distribution of amyotrophic lateral sclerosis patients with SOD-1 gene mutations: preliminary data on an Italian survey. 74
Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease 74
Synaptosomes and mitochondria from rat brain cerebral cortex: in vivo interference on some enzymatic activities by SAMe and CDP-choline 72
Towards the identification of neuroprotective agents. Pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising sigma1 receptor agonist 72
Chemical, pharmacological and in vivo pharmacokinetic studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists 72
Early alterations of mitochondrial function and morphology in the cervical spinal cord of the wobbler mouse 71
Energy metabolism inhibition impairs amyloid precursor protein secretion from Alzheimer's fibroblasts 71
Effect of chronic treatment with some drugs on the enzymatic activities of the rat brain 71
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 70
Mitochondrial function in lymphocytes from sporadic ALS and familial ALS patients 69
Studies on the enantiomers of RC-33, promising neuroprotective agents acting as sigma1 receptor agonists. Isolation, configurational assignment and biological profile 68
Use of arylalkanolamines as sigma-1 receptor antagonists 68
Sigma receptors as endoplasmic reticulum stress "gatekeepers" and their modulators as emerging new weapons in the fight against cancer 67
Phenobarbital and 6-aminonicotinamide effect on cerebral enzymatic activities related to energy metabolism in different rat brain areas 63
Modification produced by ischemia on some cerebral enzyme activities related to energy transduction 63
Implication of the antioxidant pathway in lymphocytes of sporadic amyotrophic lateral sclerosis patients 62
Mitochondrial involvement in schizophrenia and other functional psychoses 62
Effect of a ubiquinone-like molecule on oxidative energy metabolism in rat cortical synaptosomes at different ages 62
Influence of age upon the cerebral metabolic changes induced by acute hypoxia on the synaptosomes from dog brain 61
Mitochondrial energy metabolism is preserved in the lumbar spinal cord of the wobbler mouse 61
Rapid flow cytometric assessment of cell membrane integrity by Hoechst 33342 and Propidium Iodide labeling 61
Neural precursors (NPCs) from adult L967Q mice display early commitment to "in vitro" neuronal differentiation and hyperexcitability 60
Sigma1 Receptor Agonists in motor dysfunction pathologies treatment – a medicinal chemistry perspective 60
Proteomic profiling of cervical and lumbar spinal cord reveals potential protective mechanisms in the wobbler mouse, a model of motor neuron degeneration. 59
Erythropoietin protects primary motor neuron cultures from apoptotic but not necrotic death in vitro 57
Toward the identification of neuroprotective agents: G-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist 57
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 56
Effects of ionotropic glutamate receptor stimulation and mitochondrial inhibition in rat spinal cord motor neurons 56
Do lymphocytes from sporadic ALS patients show disease traits ? 54
Oxidative metabolism of non-synaptic mitochondria isolated from rat brain hippocampus: a comparative regional study 54
The effect of ischemia and pharmacological treatment evaluated on synaptosomes and purified mitochondria from rat cerebral cortex 53
Superoxide, neuroleptics and ubiquinone and cytochrome b5 reductases in brain and lymphocytes from normals and schizophrenic patients 51
Influence of aging on the acute depletion of reduced glutathione induced by electrophilic agents 47
High resolution AP-MALDI MS imaging as an aid to develop new strategies to improve ALS therapy 46
Totale 8.415
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Categoria #
all - tutte 36.588
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.588
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021447 0 0 0 0 0 96 5 94 33 104 90 25
2021/2022460 7 1 11 8 6 21 10 23 27 15 65 266
2022/20231.589 179 137 5 138 175 166 2 80 648 3 36 20
2023/2024534 85 83 10 33 49 133 13 44 4 19 50 11
2024/20251.437 23 118 45 48 55 70 40 98 354 43 168 375
2025/20261.695 273 262 410 344 373 33 0 0 0 0 0 0
Totale 8.626