IRIS
CURTI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 4.048
AS - Asia 3.015
EU - Europa 2.628
SA - Sud America 403
AF - Africa 75
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 10.175
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Nazione #
US - Stati Uniti d'America 3.966
CN - Cina 1.617
SG - Singapore 583
IE - Irlanda 542
UA - Ucraina 372
DE - Germania 314
HK - Hong Kong 307
FI - Finlandia 304
BR - Brasile 300
RU - Federazione Russa 268
IT - Italia 228
VN - Vietnam 212
FR - Francia 183
SE - Svezia 158
GB - Regno Unito 149
IN - India 87
CA - Canada 46
ZA - Sudafrica 40
AR - Argentina 39
BD - Bangladesh 38
IQ - Iraq 25
BE - Belgio 21
JP - Giappone 20
MX - Messico 20
ID - Indonesia 18
EC - Ecuador 17
ES - Italia 17
CO - Colombia 16
PL - Polonia 14
TR - Turchia 14
PH - Filippine 13
PK - Pakistan 13
NL - Olanda 11
SA - Arabia Saudita 11
LT - Lituania 10
VE - Venezuela 10
MA - Marocco 9
UZ - Uzbekistan 9
MY - Malesia 6
CL - Cile 5
KE - Kenya 5
PE - Perù 5
PY - Paraguay 5
AT - Austria 4
CZ - Repubblica Ceca 4
EG - Egitto 4
IL - Israele 4
JM - Giamaica 4
KZ - Kazakistan 4
TN - Tunisia 4
AU - Australia 3
AZ - Azerbaigian 3
CH - Svizzera 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
IR - Iran 3
KG - Kirghizistan 3
KR - Corea 3
LU - Lussemburgo 3
MU - Mauritius 3
NI - Nicaragua 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
BO - Bolivia 2
BY - Bielorussia 2
CG - Congo 2
DZ - Algeria 2
EE - Estonia 2
ET - Etiopia 2
GE - Georgia 2
GY - Guiana 2
JO - Giordania 2
KH - Cambogia 2
LV - Lettonia 2
PA - Panama 2
PT - Portogallo 2
RO - Romania 2
RS - Serbia 2
SY - Repubblica araba siriana 2
UY - Uruguay 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
CI - Costa d'Avorio 1
CY - Cipro 1
EU - Europa 1
GI - Gibilterra 1
GR - Grecia 1
HR - Croazia 1
HU - Ungheria 1
KW - Kuwait 1
LB - Libano 1
LC - Santa Lucia 1
LK - Sri Lanka 1
ML - Mali 1
MN - Mongolia 1
MZ - Mozambico 1
NP - Nepal 1
Totale 10.166
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Città #
Chandler 570
Dublin 542
Jacksonville 445
San Jose 413
Nanjing 371
Ashburn 339
Singapore 312
Beijing 311
Hong Kong 302
Dallas 217
Boardman 170
Nanchang 137
Los Angeles 113
Princeton 105
Lawrence 104
Hebei 98
Shenyang 97
Helsinki 96
Lauterbourg 94
Changsha 92
Jiaxing 87
Munich 86
Medford 79
Wilmington 79
Ann Arbor 75
Ho Chi Minh City 72
New York 63
Pavia 57
Milan 56
Buffalo 54
Tianjin 54
Hanoi 49
Shanghai 49
Moscow 48
Hangzhou 45
São Paulo 44
Council Bluffs 41
Orem 34
Johannesburg 32
Piscataway 31
Verona 30
Woodbridge 27
Redondo Beach 23
Santa Clara 23
Toronto 20
The Dalles 19
Tokyo 19
Chennai 18
Norwalk 18
Turku 18
Brussels 17
Montreal 17
Seattle 17
Pune 16
Stockholm 15
Chicago 14
Denver 13
Houston 13
Haiphong 12
London 12
Warsaw 12
Atlanta 11
Falkenstein 11
Frankfurt am Main 11
San Francisco 11
Brooklyn 10
Columbus 10
Curitiba 10
Poplar 10
Rome 10
Baghdad 9
Boston 9
Da Nang 9
Falls Church 9
Guangzhou 9
Mexico City 9
Mumbai 9
Rio de Janeiro 9
Tashkent 9
Amsterdam 8
Basingstoke 8
Brasília 8
Couilly-pont-aux-dames 8
Jinan 8
Manchester 8
Phoenix 8
Fairfield 7
Hải Dương 7
Zhengzhou 7
Ankara 6
Auburn Hills 6
Jakarta 6
Kunming 6
Quito 6
Shijiazhuang 6
Washington 6
Campinas 5
Des Moines 5
Duque de Caxias 5
Jeddah 5
Totale 6.750
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Nome #
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 162
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 147
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 146
Analysis of the early mitochondrial damage in G93A-SOD1 transgenic mice (SOD1-TG) 144
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 144
SOD1 activity and protective factors in familial ALS patients with L84F SOD1 mutation 144
A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells. 142
Clustering of ALS patients in central Italy due to the occurrence of the L84F SOD1 gene mutation 139
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 139
Age-dependent modification of drug interference on the enzymatic activities of the rat brain 136
Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes 129
Age-related acute depletion of cerebral glutathione by peroxidative stress 129
Age-related modification of enzyme activities in synaptosomes isolated from rat cerebral cortex 126
Early effects of AZT on mitochondrial functions in the absence of mitochondrial DNA depletetion in rat myotubes 126
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 126
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 126
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 123
Modified expression of Bcl-2 and SOD1 proteins in lymphocytes from sporadic ALS patients 121
SOD1 activity and protective factors in familial ALS patients with L84F SOD1 mutation 120
Mitochondrial oxidative metabolism in motor neuron degeneration (mnd) mouse central nervous system 118
Effect of ischemia and pharmacological treatment on subcellular from neonatal rat brain 118
Brain enzyme adaptation to mild normobaric intermittent hypoxia 118
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 117
Apoptosis or necrosis in motoneurons: intracellular responses to excitotoxic insults 116
Are sigma receptor modulators a weapon against multiple sclerosis disease? 116
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 114
Basic and clinical research on amyotrophic lateral sclerosis and other motor neuron disorders in Italy: recent findings and achievements from a network of laboratories 114
Effect of hypoxia on brain energy metabolism during aging 114
Heterogeneous distribution of amyotrophic lateral sclerosis patient with SOD-1 gene mulations: preliminary data on an Italian survey 112
Effect of hypoxia and pharmacological treatment on some enzyme activities in dog brain areas 112
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 111
Astrocytes derived from neural precursor cells of wobbler mice induce apoptotic death of motor neurons through reduced glutamate transport 110
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 109
Effect of prolonged and intermittent hypoxia on some cerebral enzymatic activities related to energy transduction 108
Effect of vincamine on some enzymatic activities from various areas of the beagle dog cerebral cortex 108
Kinetics of irreversible inhibition of choline transport in synaptosomes by ethylcholine mustard aziridinium 107
Alteration of pallidal cholinergic activity in MPTP-treated monkeys: effect of dihydro-alpha-ergocryptine (DEK) 106
Alteration of complex IV and acethylcholine-related enzymes in experimental spinal cord injury 106
Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients 105
Dose/action and time/action relationships of some biological molecules evaluated on the cerebral enzymatic activities 105
Effect of Ca2+-homopantothenate and mild hypoxia on some enzyme activities evaluated in subcellular fractions from different rat brain regions 105
Influence of intermittent hypoxia and pyrimidinic nucleosides on cerebral enzymatic activities related to energy transduction 104
Amyotrophic lateral sclerosis and SOD1 gene: an overview 104
Effect of aging and acetyl-L-carnitine on energetic and cholinergic metabolism in rat brain regions 103
Age-related modifications of cytochrome C oxidase activity in discrete brain regions 102
Drug interference on the age-dependent modification of the cerebral enzymatic activities related to energy transduction 102
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 101
Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells 100
Cerebral enzymatic activities during chronic hyperammonemia and treatment with S-adenosyl-L-methionine, adenosine and methionine in the rat 100
S-Adenosyl-L-methionine, related compounds, and cerebral enzymatic activities during chronic hyperammonemia in rats 99
Characterisation of adult neural stem cells from wobbler motor neuron disease mice 99
Sequential damage in mitochondrial complexes by peroxidative stress 98
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 97
Modified expression of antioxidant enzymes in lymphocytes of sporadic amyotrophic lateral sclerosis patients 96
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 96
Endothelin B receptor antagonists block proliferation and induce apoptosis in glioma cells 96
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 95
Enzymes related to energy metabolism in human gliomas 94
Mitochondrial dysfunction in a murine model of motor neuron disease 93
Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake 93
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 92
Les modifications enzymatiques du cerveau age chez le rat 91
Effect of chronic treatment with some drugs on the enzymatic activities of the rat brain 91
Mitochondrial alterations in asymptomatic G93A-SOD1 transgenic mice (SOD1-TG) 89
Chemical, pharmacological and in vivo pharmacokinetic studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists 89
Role of cerebral enzymatic activities in the relationships between energy metabolism and amino acid acting as neurotrasmitters 88
Synaptosomes and mitochondria from rat brain cerebral cortex: in vivo interference on some enzymatic activities by SAMe and CDP-choline 88
Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease 87
Use of arylalkanolamines as sigma-1 receptor antagonists 87
The mitochondrial electron transfer alteration as a factor involved in the brain aging 87
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain 86
Heterogeneous distribution of amyotrophic lateral sclerosis patients with SOD-1 gene mutations: preliminary data on an Italian survey. 85
Early alterations of mitochondrial function and morphology in the cervical spinal cord of the wobbler mouse 83
Rapid flow cytometric assessment of cell membrane integrity by Hoechst 33342 and Propidium Iodide labeling 83
Mitochondrial function in lymphocytes from sporadic ALS and familial ALS patients 83
Energy metabolism inhibition impairs amyloid precursor protein secretion from Alzheimer's fibroblasts 82
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084,in a mouse model of motor neuron disease not linked to SOD1 mutation 82
Towards the identification of neuroprotective agents. Pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising sigma1 receptor agonist 82
Experimental diets for the prevention of the development of familial amyotrophic lateral sclerosis 81
Studies on the enantiomers of RC-33, promising neuroprotective agents acting as sigma1 receptor agonists. Isolation, configurational assignment and biological profile 81
Mitochondrial involvement in schizophrenia and other functional psychoses 78
Toward the identification of neuroprotective agents: G-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist 77
Phenobarbital and 6-aminonicotinamide effect on cerebral enzymatic activities related to energy metabolism in different rat brain areas 76
Sigma receptors as endoplasmic reticulum stress "gatekeepers" and their modulators as emerging new weapons in the fight against cancer 76
Modification produced by ischemia on some cerebral enzyme activities related to energy transduction 73
Influence of age upon the cerebral metabolic changes induced by acute hypoxia on the synaptosomes from dog brain 72
Implication of the antioxidant pathway in lymphocytes of sporadic amyotrophic lateral sclerosis patients 72
Sigma1 Receptor Agonists in motor dysfunction pathologies treatment – a medicinal chemistry perspective 71
Effect of a ubiquinone-like molecule on oxidative energy metabolism in rat cortical synaptosomes at different ages 71
Neural precursors (NPCs) from adult L967Q mice display early commitment to "in vitro" neuronal differentiation and hyperexcitability 70
Mitochondrial energy metabolism is preserved in the lumbar spinal cord of the wobbler mouse 69
Erythropoietin protects primary motor neuron cultures from apoptotic but not necrotic death in vitro 69
Effects of ionotropic glutamate receptor stimulation and mitochondrial inhibition in rat spinal cord motor neurons 68
The effect of ischemia and pharmacological treatment evaluated on synaptosomes and purified mitochondria from rat cerebral cortex 68
Proteomic profiling of cervical and lumbar spinal cord reveals potential protective mechanisms in the wobbler mouse, a model of motor neuron degeneration. 66
Oxidative metabolism of non-synaptic mitochondria isolated from rat brain hippocampus: a comparative regional study 64
Do lymphocytes from sporadic ALS patients show disease traits ? 61
Superoxide, neuroleptics and ubiquinone and cytochrome b5 reductases in brain and lymphocytes from normals and schizophrenic patients 60
Influence of aging on the acute depletion of reduced glutathione induced by electrophilic agents 59
Role of synaptosomal enzymatic alterations and drug treatment in brain aging 57
Totale 9.984
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Categoria #
all - tutte 42.007
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.007
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202125 0 0 0 0 0 0 0 0 0 0 0 25
2021/2022460 7 1 11 8 6 21 10 23 27 15 65 266
2022/20231.589 179 137 5 138 175 166 2 80 648 3 36 20
2023/2024534 85 83 10 33 49 133 13 44 4 19 50 11
2024/20251.437 23 118 45 48 55 70 40 98 354 43 168 375
2025/20263.313 273 262 410 344 373 170 651 123 326 229 85 67
Totale 10.244