IRIS
MATTEVI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 4.998
EU - Europa 3.366
AS - Asia 2.478
SA - Sud America 11
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 10.866
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Nazione #
US - Stati Uniti d'America 4.973
CN - Cina 2.194
IE - Irlanda 1.247
UA - Ucraina 521
FI - Finlandia 463
DE - Germania 333
IT - Italia 290
SG - Singapore 214
GB - Regno Unito 177
SE - Svezia 161
FR - Francia 74
BE - Belgio 52
IN - India 26
CA - Canada 24
GR - Grecia 18
IR - Iran 13
NL - Olanda 12
JP - Giappone 10
CL - Cile 8
MU - Mauritius 5
TH - Thailandia 5
AT - Austria 4
TR - Turchia 4
AU - Australia 3
EU - Europa 3
LV - Lettonia 3
DK - Danimarca 2
EG - Egitto 2
HK - Hong Kong 2
MY - Malesia 2
PE - Perù 2
PL - Polonia 2
PT - Portogallo 2
RU - Federazione Russa 2
AZ - Azerbaigian 1
BD - Bangladesh 1
BR - Brasile 1
CZ - Repubblica Ceca 1
EE - Estonia 1
IL - Israele 1
KG - Kirghizistan 1
KR - Corea 1
NO - Norvegia 1
PA - Panama 1
SA - Arabia Saudita 1
TW - Taiwan 1
UZ - Uzbekistan 1
Totale 10.866
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Città #
Dublin 1.235
Chandler 1.067
Jacksonville 663
Nanjing 624
Boardman 345
Beijing 299
Ashburn 264
Ann Arbor 227
Wilmington 226
Nanchang 224
Princeton 223
Lawrence 211
Shenyang 181
Hebei 177
Changsha 165
Medford 143
New York 142
Helsinki 139
Jiaxing 134
Singapore 123
Tianjin 100
Shanghai 90
Woodbridge 89
Hangzhou 81
Milan 75
Piscataway 63
Pavia 62
Verona 54
Brussels 52
Norwalk 41
Falls Church 33
Seattle 32
Los Angeles 27
Houston 25
Munich 23
Pune 20
Fairfield 19
Toronto 19
Auburn Hills 15
Tappahannock 11
Dallas 10
Redmond 10
Sacramento 10
Taizhou 10
Zhengzhou 10
Chicago 9
Jinan 9
Kunming 8
London 8
Berlin 7
Dearborn 7
Washington 7
Des Moines 6
Falkenstein 6
Redwood City 6
Changchun 5
Fuzhou 5
Guangzhou 5
Renton 5
San Francisco 5
Santa Clara 5
Varenna 5
Zanjan 5
Bangkok 4
Borås 4
Gallarate 4
Ningbo 4
San Jose 4
Tokyo 4
Detroit 3
Genoa 3
Groningen 3
Göttingen 3
Las Vegas 3
Leawood 3
Ottawa 3
Rockville 3
Voghera 3
Ypsilanti 3
Albano Laziale 2
Albuquerque 2
Arequipa 2
Cinisello Balsamo 2
Doncaster 2
Düsseldorf 2
Fayetteville 2
Forest City 2
Gunzenhausen 2
Hefei 2
Kolham 2
Lanzhou 2
Melbourne 2
Naples 2
Phoenix 2
Porto 2
Rome 2
Shanwei 2
Warsaw 2
Xi'an 2
Yaraichō 2
Totale 8.002
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Nome #
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells 100
Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces coelicolor Alditol Oxidase 88
Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis 88
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation. 87
A Novel Mammalian Flavin-dependent Histone Demethylase 86
Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies 84
The 'gating' residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition. 81
A 30-angstrom-long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase 80
Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformationand support novel mechanism of action 78
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities. 78
Structure of the mutant E92K of [2Fe-2S] ferredoxin I from Spinacia oleracea at 1.7 A resolution. 77
Active site plasticity in D-amino acid oxidase: a crystallographic analysis. 77
ThermoFAD, a Thermofluor®-adapted flavin ad hoc detection system for protein folding and ligand binding 76
Asp-170 is crucial for the redox properties of vanillyl-alcohol oxidase. 76
Crystallization and preliminary X-ray analysis of the flavoenzyme vanillyl-alcohol oxidase from Penicillium simplicissimum. 74
Structure of L-aspartate oxidase: implications for the succinate dehydrogenase/fumarate reductase oxidoreductase family 74
The active conformation of glutamate synthase and its binding to ferredoxin 73
A combined computational and biochemical analysis of oxygen diffusion and reactivity in a flavoprotein monooxygenase and oxidase 73
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia 73
Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B 72
Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin. 72
Binding of Rasagiline-related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis 71
Enzymes Without Borders: Mobilizing Substrates, Delivering Products 71
Recombinant pyruvate kinase type I from Escherichia coli:overproduction and revised C-terminus of the polypeptide 70
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 70
Crystallization and preliminary X-ray analysis of an alditol oxidase from Streptomyces coelicolor A3(2) 69
Crystallization of L-aspartate oxidase, the first enzyme in the bacterial de novo biosynthesis of NAD. 67
Structure of FAD-bound L-aspartate oxidase: insight into substrate specificity and catalysis 67
Structure of D-amino acid oxidase: new insights from an old enzyme 67
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class 67
Structure-basedredesign of cofactor binding in putrescine oxidase 67
Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase 67
Crystallization and preliminary X-ray analysis of pyruvate kinase type I from Escherichia coli. 67
Structural and biochemical evaluation of Ceratitis capitata OBP22 affinity for odorants involved in inter-sex communication 67
Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs 66
The crucial step in ether phospholipid biosynthesis: structural basis of a non-canonical reaction associated to a peroxisomal disorder 66
A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase 66
X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states 65
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 65
8 Demethylation pathways for histone methyllysine residues 65
Structural characterization of l-aspartate oxidase and identification of an interdomain loop by limited proteolysis. 64
A novel oxidoreductase family sharing a conserved FAD-binding domain 64
Crystal structures and atomic model of NADPH oxidase 64
Alternative Splicing of the Histone Demethylase LSD1/KDM1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System 64
Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane 63
TRANYLCYPROMINE DERIVATIVES AS INHIBITORS OF HISTONE DEMETHYLASE LSD1 AND/OR LSD2 63
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition 63
Flavins as Covalent Catalysts: New Mechanisms Emerge 63
Purification and crystallization of Kokobera virus helicase 62
Structure of the monooxygenase component of a two-component flavoprotein monooxygenase 62
The FAD Binding Sites of Human Monoamine Oxidases A and B 62
Functional Role of the "Aromatic Cage" in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins. 61
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates 61
A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1 61
A monotopic membrane protein goes solo 60
Structure of the human mitochondrial monoamine oxidase B: New chemical implications for neuroprotectant drug design 60
The role of the proteome in catalysis and regulation 60
Histone Demethylation Catalysed by LSD1 is a Flavin-dependent Oxidative Process 60
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features 60
Human erythrocyte pyruvate kinase:characterization of the recombinant enzyme and a mutant form(R510Q))causing nonspherocytic hemolytic anemia. 60
A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action 60
Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase. 59
Engineering of microheterogeneity-resistant p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens 58
Characterization of a pyrimidine 5'-nucleotidase mutant form (G214R) causing hereditary hemolytic anemia. 58
Bringing proteins to life 57
Inversion of stereospecificity and regain of covalent flavinylation of vanillyl-alcohol oxidase 57
A close look at NAD biosynthesis 57
The allosteric regulation of pyruvate kinase 57
Limited proteolysis and X-ray crystallography reveal the origin of substrate specificity and of the rate-limiting product release during oxidation of D-amino acids catalyzed by mammalian D-amino acid oxidase 57
Finding the Switch: Turning a Baeyer-Villiger Monooxygenase into a NADPH Oxidase. 57
The allosteric regulation of pyruvate kinase. 57
Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis 57
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex 57
Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases 57
Polystyrene microbridges used in sitting-drop crystallisation release 1,4-diphenyl-2-butene, a novel inhibitor of human MAO B 56
To be or not to be an oxidase: challenging the oxygen reactivity of flavoenzymes 56
The PHBH fold: not only flavoenzymes 56
Structural Basis of LSD1-CoREST Selectivity in Histone H3 Recognition 56
Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p) 56
Protein Recognition by Short Peptide Reversible Inhibitors of the Chromatin-Modifying LSD1/CoREST Lysine Demethylase. 56
Covalent flavinylation is essential for efficient redox catalysis in vanillyl-alcohol oxidase 55
Structural analysis of flavinylation in vanillyl-alcohol oxidase 55
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent 55
New frontiers in structural flavoenzymology 54
Refined crystal structure of the catalytic domain of dihydrolipoyl transacetylase (E2p) from Azotobacter vinelandii at 2.6 A resolution 54
New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin. 54
LSD1: Oxidative Chemistry for Multifaceted Functions in Chromatin Regulation. 54
Glutamate Synthase: a fascinating pathway from L-glutamine to glutamate 54
MUTATED FORM OF NADPH OXIDASES 54
Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes 54
New structures of allosteric proteins revealing remarkable conformational changes 54
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. 54
Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs 53
Crystallization and preliminary X-ray analysis of polyamine oxidase from Zea mays L. 53
An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation 53
Cyclization in concert. 52
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis 52
Flavoenzymes:diverse catalysts with recurrent features 51
Structure and biochemical analysis of Kokobera virus helicase. 51
Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders 51
Totale 6.392
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Categoria #
all - tutte 50.060
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.060
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020700 0 0 0 0 13 97 34 106 18 187 228 17
2020/20211.088 123 95 28 102 17 129 21 208 57 160 120 28
2021/2022895 23 10 19 11 25 22 35 59 58 33 129 471
2022/20233.255 353 225 42 240 300 308 5 176 1.458 24 86 38
2023/20241.225 208 196 37 79 110 324 11 67 15 37 108 33
2024/2025581 96 278 63 91 53 0 0 0 0 0 0 0
Totale 11.211