IRIS
MATTEVI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 4.734
EU - Europa 3.318
AS - Asia 2.276
SA - Sud America 8
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 10.349
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Nazione #
US - Stati Uniti d'America 4.710
CN - Cina 2.167
IE - Irlanda 1.247
UA - Ucraina 521
FI - Finlandia 462
DE - Germania 302
IT - Italia 286
GB - Regno Unito 173
SE - Svezia 161
FR - Francia 74
BE - Belgio 51
SG - Singapore 46
IN - India 26
CA - Canada 24
GR - Grecia 18
IR - Iran 13
NL - Olanda 11
JP - Giappone 9
CL - Cile 8
MU - Mauritius 5
AU - Australia 3
EU - Europa 3
LV - Lettonia 3
TH - Thailandia 3
DK - Danimarca 2
EG - Egitto 2
HK - Hong Kong 2
MY - Malesia 2
PT - Portogallo 2
RU - Federazione Russa 2
TR - Turchia 2
AT - Austria 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CZ - Repubblica Ceca 1
EE - Estonia 1
IL - Israele 1
KR - Corea 1
SA - Arabia Saudita 1
UZ - Uzbekistan 1
Totale 10.349
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Città #
Dublin 1.235
Chandler 1.067
Jacksonville 663
Nanjing 624
Beijing 297
Ashburn 262
Ann Arbor 227
Wilmington 226
Nanchang 224
Princeton 223
Lawrence 211
Shenyang 181
Hebei 177
Changsha 165
Medford 143
New York 142
Helsinki 138
Jiaxing 134
Boardman 111
Tianjin 100
Shanghai 90
Woodbridge 89
Hangzhou 81
Milan 72
Piscataway 63
Pavia 62
Verona 54
Brussels 51
Norwalk 41
Falls Church 33
Seattle 31
Houston 25
Los Angeles 25
Singapore 25
Pune 20
Fairfield 19
Toronto 19
Auburn Hills 15
Tappahannock 11
Redmond 10
Sacramento 10
Taizhou 10
Chicago 9
Kunming 8
Zhengzhou 8
Dearborn 7
Washington 7
Berlin 6
Des Moines 6
Falkenstein 6
Jinan 6
Redwood City 6
Changchun 5
Fuzhou 5
London 5
Renton 5
San Francisco 5
Varenna 5
Zanjan 5
Borås 4
Gallarate 4
Guangzhou 4
Ningbo 4
San Jose 4
Tokyo 4
Detroit 3
Genoa 3
Groningen 3
Las Vegas 3
Leawood 3
Ottawa 3
Rockville 3
Santa Clara 3
Voghera 3
Ypsilanti 3
Albano Laziale 2
Albuquerque 2
Bangkok 2
Cinisello Balsamo 2
Dallas 2
Doncaster 2
Düsseldorf 2
Forest City 2
Gunzenhausen 2
Kolham 2
Lanzhou 2
Melbourne 2
Naples 2
Phoenix 2
Porto 2
Rome 2
Xi'an 2
Yaraichō 2
Apo 1
At Tuwal 1
Augusta 1
Bari 1
Bloomfield 1
Bologna 1
Brescia 1
Totale 7.607
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Nome #
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells 97
Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis 86
Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces coelicolor Alditol Oxidase 84
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation. 84
Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies 82
A Novel Mammalian Flavin-dependent Histone Demethylase 80
The 'gating' residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition. 80
A 30-angstrom-long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase 79
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities. 77
Structure of the mutant E92K of [2Fe-2S] ferredoxin I from Spinacia oleracea at 1.7 A resolution. 76
Active site plasticity in D-amino acid oxidase: a crystallographic analysis. 75
Asp-170 is crucial for the redox properties of vanillyl-alcohol oxidase. 75
ThermoFAD, a Thermofluor®-adapted flavin ad hoc detection system for protein folding and ligand binding 73
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia 72
Structure of L-aspartate oxidase: implications for the succinate dehydrogenase/fumarate reductase oxidoreductase family 72
Crystallization and preliminary X-ray analysis of the flavoenzyme vanillyl-alcohol oxidase from Penicillium simplicissimum. 71
The active conformation of glutamate synthase and its binding to ferredoxin 71
Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B 69
A combined computational and biochemical analysis of oxygen diffusion and reactivity in a flavoprotein monooxygenase and oxidase 69
Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin. 69
Binding of Rasagiline-related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis 68
Recombinant pyruvate kinase type I from Escherichia coli:overproduction and revised C-terminus of the polypeptide 68
Crystallization and preliminary X-ray analysis of an alditol oxidase from Streptomyces coelicolor A3(2) 66
Enzymes Without Borders: Mobilizing Substrates, Delivering Products 66
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 66
Crystallization of L-aspartate oxidase, the first enzyme in the bacterial de novo biosynthesis of NAD. 65
A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase 65
Structure of D-amino acid oxidase: new insights from an old enzyme 64
Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformationand support novel mechanism of action 64
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class 64
Structure-basedredesign of cofactor binding in putrescine oxidase 64
Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs 64
8 Demethylation pathways for histone methyllysine residues 64
Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase 64
Structure of FAD-bound L-aspartate oxidase: insight into substrate specificity and catalysis 63
X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states 63
The crucial step in ether phospholipid biosynthesis: structural basis of a non-canonical reaction associated to a peroxisomal disorder 63
Crystallization and preliminary X-ray analysis of pyruvate kinase type I from Escherichia coli. 63
Structural and biochemical evaluation of Ceratitis capitata OBP22 affinity for odorants involved in inter-sex communication 63
Structural characterization of l-aspartate oxidase and identification of an interdomain loop by limited proteolysis. 62
A novel oxidoreductase family sharing a conserved FAD-binding domain 62
Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane 62
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 61
Crystal structures and atomic model of NADPH oxidase 61
Flavins as Covalent Catalysts: New Mechanisms Emerge 61
Purification and crystallization of Kokobera virus helicase 60
TRANYLCYPROMINE DERIVATIVES AS INHIBITORS OF HISTONE DEMETHYLASE LSD1 AND/OR LSD2 60
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates 60
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition 60
Functional Role of the "Aromatic Cage" in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins. 59
Structure of the monooxygenase component of a two-component flavoprotein monooxygenase 59
Human erythrocyte pyruvate kinase:characterization of the recombinant enzyme and a mutant form(R510Q))causing nonspherocytic hemolytic anemia. 59
Structure of the human mitochondrial monoamine oxidase B: New chemical implications for neuroprotectant drug design 58
Histone Demethylation Catalysed by LSD1 is a Flavin-dependent Oxidative Process 58
Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase. 58
The FAD Binding Sites of Human Monoamine Oxidases A and B 58
A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1 58
A monotopic membrane protein goes solo 57
The role of the proteome in catalysis and regulation 57
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features 57
Alternative Splicing of the Histone Demethylase LSD1/KDM1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System 57
Inversion of stereospecificity and regain of covalent flavinylation of vanillyl-alcohol oxidase 56
Engineering of microheterogeneity-resistant p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens 56
Limited proteolysis and X-ray crystallography reveal the origin of substrate specificity and of the rate-limiting product release during oxidation of D-amino acids catalyzed by mammalian D-amino acid oxidase 56
Characterization of a pyrimidine 5'-nucleotidase mutant form (G214R) causing hereditary hemolytic anemia. 56
A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action 56
Bringing proteins to life 55
The allosteric regulation of pyruvate kinase 55
Finding the Switch: Turning a Baeyer-Villiger Monooxygenase into a NADPH Oxidase. 55
The allosteric regulation of pyruvate kinase. 55
Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis 55
A close look at NAD biosynthesis 54
Structural Basis of LSD1-CoREST Selectivity in Histone H3 Recognition 54
Covalent flavinylation is essential for efficient redox catalysis in vanillyl-alcohol oxidase 54
Protein Recognition by Short Peptide Reversible Inhibitors of the Chromatin-Modifying LSD1/CoREST Lysine Demethylase. 54
Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases 54
To be or not to be an oxidase: challenging the oxygen reactivity of flavoenzymes 53
The PHBH fold: not only flavoenzymes 53
Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p) 53
Refined crystal structure of the catalytic domain of dihydrolipoyl transacetylase (E2p) from Azotobacter vinelandii at 2.6 A resolution 53
Structural analysis of flavinylation in vanillyl-alcohol oxidase 53
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex 53
Polystyrene microbridges used in sitting-drop crystallisation release 1,4-diphenyl-2-butene, a novel inhibitor of human MAO B 52
New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin. 52
Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes 52
New structures of allosteric proteins revealing remarkable conformational changes 52
LSD1: Oxidative Chemistry for Multifaceted Functions in Chromatin Regulation. 51
Glutamate Synthase: a fascinating pathway from L-glutamine to glutamate 51
MUTATED FORM OF NADPH OXIDASES 51
Crystallization and preliminary X-ray analysis of polyamine oxidase from Zea mays L. 51
An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation 51
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent 51
New frontiers in structural flavoenzymology 50
Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs 50
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis 50
Flavoenzymes:diverse catalysts with recurrent features 49
Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders 49
Cyclization in concert. 49
The catalytic domain of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii and Escherichia coli. Expression, purification, properties and preliminary X-ray analysis 49
Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase 49
Totale 6.124
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Categoria #
all - tutte 42.261
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.261
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.521 764 959 5 93 13 97 34 106 18 187 228 17
2020/20211.088 123 95 28 102 17 129 21 208 57 160 120 28
2021/2022895 23 10 19 11 25 22 35 59 58 33 129 471
2022/20233.255 353 225 42 240 300 308 5 176 1.458 24 86 38
2023/20241.225 208 196 37 79 110 324 11 67 15 37 108 33
2024/202559 59 0 0 0 0 0 0 0 0 0 0 0
Totale 10.689