IRIS
MATTEVI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 9.432
AS - Asia 6.955
EU - Europa 5.152
SA - Sud America 1.100
Continente sconosciuto - Info sul continente non disponibili 399
AF - Africa 320
OC - Oceania 10
Totale 23.368
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Nazione #
US - Stati Uniti d'America 9.145
CN - Cina 3.234
SG - Singapore 1.539
IE - Irlanda 1.255
HK - Hong Kong 829
BR - Brasile 814
RU - Federazione Russa 646
VN - Vietnam 601
FI - Finlandia 544
UA - Ucraina 543
DE - Germania 524
IT - Italia 473
FR - Francia 349
GB - Regno Unito 300
ZA - Sudafrica 198
SE - Svezia 197
IN - India 179
CA - Canada 129
AR - Argentina 113
BD - Bangladesh 103
MX - Messico 90
BE - Belgio 64
JP - Giappone 50
PL - Polonia 50
IQ - Iraq 46
TR - Turchia 46
NL - Olanda 44
ID - Indonesia 43
EC - Ecuador 42
CO - Colombia 36
ES - Italia 33
PK - Pakistan 31
SA - Arabia Saudita 29
AT - Austria 27
PH - Filippine 26
GR - Grecia 24
UZ - Uzbekistan 24
VE - Venezuela 24
MA - Marocco 23
CL - Cile 20
MY - Malesia 20
PE - Perù 19
TN - Tunisia 19
IR - Iran 18
PY - Paraguay 16
KE - Kenya 14
LT - Lituania 14
EG - Egitto 13
AE - Emirati Arabi Uniti 12
AZ - Azerbaigian 12
JO - Giordania 12
KR - Corea 12
PA - Panama 11
TH - Thailandia 11
DZ - Algeria 10
ET - Etiopia 10
BO - Bolivia 9
IL - Israele 9
JM - Giamaica 9
LV - Lettonia 9
NP - Nepal 9
DO - Repubblica Dominicana 8
PS - Palestinian Territory 8
PT - Portogallo 8
AU - Australia 7
CI - Costa d'Avorio 7
CR - Costa Rica 7
OM - Oman 7
TT - Trinidad e Tobago 7
TW - Taiwan 7
BH - Bahrain 6
CH - Svizzera 6
CZ - Repubblica Ceca 6
KG - Kirghizistan 6
MU - Mauritius 6
UY - Uruguay 6
DK - Danimarca 5
EE - Estonia 5
KZ - Kazakistan 5
NI - Nicaragua 5
SN - Senegal 5
SY - Repubblica araba siriana 5
BG - Bulgaria 4
GT - Guatemala 4
HN - Honduras 4
AM - Armenia 3
BS - Bahamas 3
EU - Europa 3
GA - Gabon 3
KH - Cambogia 3
ME - Montenegro 3
SV - El Salvador 3
AL - Albania 2
AO - Angola 2
BB - Barbados 2
BW - Botswana 2
BY - Bielorussia 2
HR - Croazia 2
HU - Ungheria 2
LK - Sri Lanka 2
Totale 22.936
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Città #
Dublin 1.242
Chandler 1.067
San Jose 910
Hong Kong 811
Singapore 811
Ashburn 779
Beijing 663
Jacksonville 663
Nanjing 628
Dallas 484
Boardman 353
Council Bluffs 320
New York 241
Los Angeles 238
Ann Arbor 227
Wilmington 226
Nanchang 224
Princeton 223
Lawrence 211
Ho Chi Minh City 209
Lauterbourg 206
Shenyang 183
Helsinki 180
Changsha 178
Hebei 177
Johannesburg 176
Hanoi 144
Medford 143
Jiaxing 135
Buffalo 130
Moscow 128
Munich 117
Santa Clara 111
Tianjin 111
Shanghai 102
Milan 99
Woodbridge 89
Hangzhou 87
Redondo Beach 84
Pavia 80
São Paulo 76
Piscataway 67
Orem 66
The Dalles 64
Brussels 62
Verona 54
Warsaw 44
Mexico City 41
Norwalk 41
Houston 40
Turku 40
Chicago 39
Seattle 39
Tokyo 39
Montreal 36
Toronto 36
Columbus 35
Frankfurt am Main 35
Stockholm 34
Falls Church 33
San Francisco 33
Rio de Janeiro 31
Brooklyn 30
Falkenstein 30
Chennai 29
Denver 29
Atlanta 28
London 28
Haiphong 26
Phoenix 26
Da Nang 24
Rome 23
Zhengzhou 23
Pune 22
Tashkent 22
Boston 21
Curitiba 21
Manchester 21
Nuremberg 21
Poplar 21
Fairfield 19
Mumbai 19
Guangzhou 18
Ankara 17
Biên Hòa 16
Brasília 16
Quito 16
Auburn Hills 15
Baghdad 15
Belo Horizonte 15
Guayaquil 15
Amsterdam 14
Hyderabad 14
Jinan 14
Memphis 14
Campinas 13
Jeddah 13
Paris 13
Lahore 12
Amman 11
Totale 14.919
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Nome #
Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformationand support novel mechanism of action 180
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation. 170
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells 165
A Novel Mammalian Flavin-dependent Histone Demethylase 165
Touch, act and go: Landing and operating on nucleosomes 162
A 30-angstrom-long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase 153
Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces coelicolor Alditol Oxidase 149
A combined computational and biochemical analysis of oxygen diffusion and reactivity in a flavoprotein monooxygenase and oxidase 148
Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis 148
The crucial step in ether phospholipid biosynthesis: structural basis of a non-canonical reaction associated to a peroxisomal disorder 144
The 'gating' residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition. 144
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 144
A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action 141
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. 140
Crystal structures and atomic model of NADPH oxidase 138
8 Demethylation pathways for histone methyllysine residues 137
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship 136
Active site plasticity in D-amino acid oxidase: a crystallographic analysis. 135
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 132
Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies 132
Structure of the mutant E92K of [2Fe-2S] ferredoxin I from Spinacia oleracea at 1.7 A resolution. 131
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities. 130
Crystallization and preliminary X-ray analysis of an alditol oxidase from Streptomyces coelicolor A3(2) 129
Crystallization and preliminary X-ray analysis of pyruvate kinase type I from Escherichia coli. 129
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex 129
Binding of Rasagiline-related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis 128
Structure of L-aspartate oxidase: implications for the succinate dehydrogenase/fumarate reductase oxidoreductase family 128
Structural and biochemical evaluation of Ceratitis capitata OBP22 affinity for odorants involved in inter-sex communication 128
MUTATED FORM OF NADPH OXIDASES 127
Structure-basedredesign of cofactor binding in putrescine oxidase 125
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition 125
Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin. 125
Crystallization and preliminary X-ray analysis of the flavoenzyme vanillyl-alcohol oxidase from Penicillium simplicissimum. 124
Alternative Splicing of the Histone Demethylase LSD1/KDM1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System 124
The growing structural and functional complexity of the LSD1/KDM1A histone demethylase 123
A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1 123
Asp-170 is crucial for the redox properties of vanillyl-alcohol oxidase. 123
STRUCTURE AND MECHANISM OF MONOAMINE OXIDASE 122
A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase 122
The allosteric regulation of pyruvate kinase. 121
Recombinant pyruvate kinase type I from Escherichia coli:overproduction and revised C-terminus of the polypeptide 120
Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs 120
Enzymes Without Borders: Mobilizing Substrates, Delivering Products 120
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features 120
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates 119
Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations 118
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class 116
ThermoFAD, a Thermofluor®-adapted flavin ad hoc detection system for protein folding and ligand binding 115
Crystal Structure of a Baeyer-Villiger Monooxygenase. 115
New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin. 114
Flavins as Covalent Catalysts: New Mechanisms Emerge 113
A novel oxidoreductase family sharing a conserved FAD-binding domain 111
Characterization of a pyrimidine 5'-nucleotidase mutant form (G214R) causing hereditary hemolytic anemia. 111
A monotopic membrane protein goes solo 110
Protein Recognition by Short Peptide Reversible Inhibitors of the Chromatin-Modifying LSD1/CoREST Lysine Demethylase. 110
Structure of the monooxygenase component of a two-component flavoprotein monooxygenase 110
Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring 110
Structural and biochemical insights into 7β-hydroxysteroid dehydrogenase stereoselectivity 110
The active conformation of glutamate synthase and its binding to ferredoxin 109
The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases 109
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells 109
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia 108
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A. 108
Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans 108
An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation 108
A close look at NAD biosynthesis 107
Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer 107
A cross-talk and amonia channeling between active in the unexpected domain arrangement of glutamate synthase. 106
New frontiers in structural flavoenzymology 105
Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane 105
Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B 105
Crystallization and preliminary X-ray analysis of polyamine oxidase from Zea mays L. 105
Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis 105
Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging 105
Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase 104
3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1 contains a phosphatidylinositol cofactor 104
Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism 104
Engineering stability in NADPH oxidases: A common strategy for enzyme production 104
Functional Role of the "Aromatic Cage" in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins. 103
Structure of FAD-bound L-aspartate oxidase: insight into substrate specificity and catalysis 103
Differential properties of transcriptional complexes formed by the CoREST family. 103
Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents 103
Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase 103
X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states 102
The FAD Binding Sites of Human Monoamine Oxidases A and B 102
Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst 102
In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis 101
Structural characterization of l-aspartate oxidase and identification of an interdomain loop by limited proteolysis. 101
Purification and crystallization of Kokobera virus helicase 101
Structural Insight into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases 101
Crystallization of L-aspartate oxidase, the first enzyme in the bacterial de novo biosynthesis of NAD. 100
Probing the interaction of the p53 C-terminal domain to the histone demethylase LSD1 100
Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex 99
Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes 99
LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors 99
An elegant four-helical fold in NOX and STEAP enzymes facilitates electron transport across biomembranes - Similar vehicle, different destination 99
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent 99
Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance 98
Structural Basis of LSD1-CoREST Selectivity in Histone H3 Recognition 98
Finding the Switch: Turning a Baeyer-Villiger Monooxygenase into a NADPH Oxidase. 98
Totale 11.880
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Categoria #
all - tutte 102.425
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 102.425
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022872 0 10 19 11 25 22 35 59 58 33 129 471
2022/20233.255 353 225 42 240 300 308 5 176 1.458 24 86 38
2023/20241.225 208 196 37 79 110 324 11 67 15 37 108 33
2024/20253.564 96 278 63 91 102 177 185 222 951 143 437 819
2025/20268.562 690 712 958 857 1.089 293 1.430 465 783 691 350 244
2026/2027612 211 401 0 0 0 0 0 0 0 0 0 0
Totale 23.368